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傅崇安

傅崇安 / Sebastian D. Fugmann, Ph.D.

職稱： 教授

現職： 長庚大學生物醫學研究所教授

信箱： sdfugmann@mail.cgu.edu.tw

電話： 03-2118800 #3478

學歷： 德國烏爾姆大學博士

專長領域： 免疫演化、無脊椎生物免疫

個人網頁： https://reurl.cc/VzrzOb

學歷

1998   德國烏爾姆大學人類生物學博士
1993   德國康士坦茲大學物理化學碩士
1990   德國漢堡大學化學系學士

經歷

2013-迄今    長庚大學生物醫學系教授
2019-2020   長庚大學國際事務處主任
2018-2019   長庚大學國際事務處副主任
2004-2013   美國國家衛生研究院老年研究所分子生物學與免疫學實驗室研究員
1998-2004   美國耶魯大學免疫所博士後研究員

論文與著作(選錄)

  1. Li YR, Ling LB, Chao A, Fugmann SD*, Yang SY. Transient chromatin decompaction at the start of D. melanogaster  male embryonic germline development. Life Sci Alliance. 2024 Jul 11;7(10):e202302401.
  2. Liu MC, Fugmann SD*. Measuring Mutator Enzyme Activity Using an E. coli-Based Colony Formation Assay. Methods Mol Biol. 2022;2421:103-114.
  3. Li YR, Lai HW, Huang HH, Chen HC, Fugmann SD, Yang SY. Trajectory mapping of the early Drosophila germline reveals controls of zygotic activation and sex differentiation. Genome Res. 2021 Jun;31(6):1011-1023.
  4. Liu MC, Liao WY, Buckley KM, Yang SY, Rast JP, Fugmann SD*. AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates. Nat Commun. 2018 May 16;9(1):1948.
  5. Wang XR, Ling LB, Huang HH, Lin JJ, Fugmann SD, Yang SY. Evidence for parallel evolution of a gene involved in the regulation of spermatogenesis. Proc Biol Sci. 2017 May 31;284(1855):20170324.
  6. Carmona LM, Fugmann SD, Schatz DG. Collaboration of RAG2 with RAG1-like proteins during the evolution of V(D)J recombination. Genes Dev. 2016 Apr 15;30(8):909-17.
  7. Fugmann SD*. Form follows function - the three-dimensional structure of antigen receptor gene loci. Curr Opin Immunol. 2014 Apr;27:33-7.
  8. Kothapalli NR, Collura KM, Norton DD, Fugmann SD*. Separation of mutational and transcriptional enhancers in Ig genes. J Immunol. 2011 Sep 15;187(6):3247-55.
  9. Fugmann SD*. RAG-2 unleashed: lymphocytes beware. Immunity. 2011 Feb 25;34(2):137-9.
  10. Delker RK, Fugmann SD, Papavasiliou FN. A coming-of-age story: activation-induced cytidine deaminase turns 10. Nat Immunol. 2009 Nov;10(11):1147-53.
  11. Gopal AR, Fugmann SD*. AID-mediated diversification within the IgL locus of chicken DT40 cells is restricted to the transcribed IgL gene. Mol Immunol. 2008 Apr;45(7):2062-8.
  12. Yang SY, Fugmann SD, Schatz DG. Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences. J Exp Med. 2006 Dec 25;203(13):2919-28.
  13. Fugmann SD, Messier C, Novack LA, Cameron RA, Rast JP. An ancient evolutionary origin of the Rag1/2 gene locus. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3728-33.