陳星甫 / Shin-Fu Chen
職稱： 助理教授
現職： 長庚大學生化分生科 專任教師
電話： 3199
學歷： 臺灣大學醫學院生物化學暨分子生物學研究所博士
專長領域： 生物化學、分子生物學、結構生物學
個人網頁： https://pure.lib.cgu.edu.tw/zh/persons/shin-fu-chen/
學歷
2018 臺灣大學醫學院生物化學暨分子生物學研究所博士2009 臺北醫學大學保健營養學系學士
經歷
2025-迄今 長庚大學生化暨分子生物學科 助理教授2025 臺灣大學醫學院生物化學暨分子生物學研究所；農業化學系暨研究所 博士後研究員
2019-2024 美國德州大學休士頓健康科學中心麥戈文醫學院生物化學與分子生物學系 博士後研究員
榮譽
2024 CPRIT BIG-TCR Annual Retreat, Poster Session – First Prize, Postgraduate group (2024)2024 Department of Biochemistry and Molecular Biology Annual Retreat (McGovern Medical School) – First Place, Poster
Presentation2023-2024 CPRIT BIG-TCR Postdoctoral Research Fellowship – funded by the Cancer Prevention and Research Institute of
2023 Department of Biochemistry and Molecular Biology Annual Retreat (McGovern Medical School) – Third Place, OralTexas
Presentation2022 Department of Biochemistry and Molecular Biology Annual Retreat (McGovern Medical School) – First Place, Oral Presentation
2019 Distinguished Thesis Prize, 15th TienTe Lee Biomedical Award (2019)
第十五屆永信李天德醫藥科技獎 — 傑出論文獎
2019 Outstanding Award for Postgraduate Students’ Publications, National Taiwan University College of Medicine
國立臺灣大學醫學院研究生優秀著作獎 — 107學年度博士班傑出著作獎
2017 The 23rd NSRRC (National Synchrotron Radiation Research Center) Users’ Meeting and Workshops – First Place,
Student Oral Presentation in Biological Science
近五年發表論文
1. Ti-Chun Chao†, Shin-Fu Chen†, Hee Jong Kim, Hui-Chi Tang, Hsiang-Ching Tseng, An Xu, Leon Palao 3rd, Subash Khadka, Tao Li, Mo-Fan Huang, Dung-Fang Lee, Kenji Murakami#, Thomas G Boyer#, Kuang-Lei Tsai# (2024) Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol Cell. 84(20), 3932–3949.e10 (†co first author)2. Ko-Ting Liu, Shin-Fu Chen, Nei-Li Chan (2024) Structural insights into the assembly of type IIA topoisomerase DNA cleavage-religation center. Nucleic Acids Res., gkae657.
3. Jose J Gorbea Colón†, Leon Palao III†, Shin-Fu Chen, Hee Jong Kim, Laura Snyder, Yi-Wei Chang#, Kuang-Lei Tsai#, Kenji Murakami# (2023) Structural basis of a transcription pre-initiation complex on a divergent promoter. Mol Cell. 83(4):574-588.e11. (†co first author)
4. Lindsey Barron, Subash Khadka, Robert Schenken, Long He, John Blenis, Julian Blagg, Shin-Fu Chen, Kuang-Lei Tsai, Thomas G Boyer. (2021) Identification and characterization of the mediator kinase-dependent myometrial stem cell phosphoproteome. F&S Science. Volume 2, Issue 4, Pages 383-395
5. Feng Xiong†, Ruoyu Wang†, Joo-Hyung Lee, Shenglan Li, Shin-Fu Chen, Zian Liao, Lana Al Hasani, Phuoc T Nguyen, Xiaoyu Zhu, Joanna Krakowiak, Dung-Fang Lee, Leng Han, Kuang-Lei Tsai, Ying Liu, Wenbo Li. (2021) RNA m6A modification orchestrates a LINE-1–host interaction that facilitates retrotransposition and contributes to long gene vulnerability. Cell Res. 31(8):861-885. (†co first author)
6. Yi-Chuan Li†, Ti-Chun Chao†, Hee Jong Kim, Timothy Cholko, Shin-Fu Chen, Guojie Li, Laura Snyder, Kotaro Nakanishi, Chia-en Chang, Kenji Murakami, Benjamin A Garcia, Thomas G Boyer#, Kuang-Lei Tsai#. (2021) Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module. Sci Adv. 7(3):eabd4484.