方嘉佑 / Jia-You Fang
職稱： 專任特聘教授
現職： 中醫學系天然藥物碩士班 / Full-time Distinguished Professor
電話： 分機5521
學歷： 高雄醫學大學藥學所博士
專長領域： 藥劑學、藥物標靶與傳輸、化妝品學、奈米醫學、天然物藥理活性探究
個人網頁： https://pure.lib.cgu.edu.tw/en/persons/jia-you-fang-2
研究室資料
研究室：藥劑學研究室研究室介紹連結 https://jiayoufang.pixnet.net/blog/category/131593
研究室成員：
博士班研究生3人、碩士班研究生6人、專任研究助理7人、博士後研究員1人
研究主題
藥劑學研究在日本是屬於醫療藥學領域，在歐美國家則屬藥廠研發實務，其精神在於以既定藥物賦予全新設計的處方、添加物或材料，以使藥物本身之藥理活性最大化或使其毒性及副作用最小化，或是延長藥物於體內的留存時間。其意義在於使臨床上的用藥更加安全及有效，進而改善病患之依順性。藥劑學在藥學研究領域內被視為較下游之藥物研發過程，為一門應用科學，本研究室的主要工作便是為藥物設計新的處方內容並探究其改善傳統劑型缺點之程度與能力。
最近之研究計畫:
- 多功能藥物奈米載體經由 retinol-binding protein 4 (RBP4) 傳輸至腎臟以治療抗藥性菌血症誘發之腎損傷
- 多效能之藍莓活性成分 pterostilbene 可塑性奈米微脂體：用以促進瓦解 P. acnes 生物膜結構與抗局部感染活性
- 接合 NIMP-R14 抗體的脂質奈米載體主動標靶至嗜中性白血球以改善 PDE4 抑制劑之抗乾癬活性
- 兼具被動與主動標靶能力之奈米載體傳輸 ciprofloxacin 以治療感染性肺炎：以 IsaB DNA 為配體之非離子微胞
- 設計合成含有角鯊烯之前驅藥及其奈米載體開發：以毛囊為標靶位置
- 厚朴有效成分之抗發炎及經皮吸收之研究
- 牛樟芝萃取物治療異位性皮膚炎之研究：牛樟芝單苯環類化合物在角質細胞中的抗發炎機制
- 一系列合成異黃酮類化合物之經皮吸收參數建立與其乾癬治療之活性探究
- 中草藥多酚成分之最適分離技術開發
最近之產學合作計畫:
- 中部科學園區管理局: 新劑型、新給藥方式之痤瘡 (Acne vulgaris) 用藥-美諾四環 (Minocycline)-505(b)2新藥開發
- 台塑生醫: 保養品暨美容儀器經皮吸收及功效性研究
- 肌活麗學創研所: 乳鐵蛋白抗白髮胜肽經皮吸收
- 大江生醫: LipoMask 之經皮吸收能力評估
- 生達化學製藥: VD-T03 處方優化與物理化學性質評估
- 信東製藥: 硬鏡去蛋白試驗
- 元太科技: 新型藥物貼片平台經皮膚傳導能力可行性
- 藥華醫藥: KX-01牛皮癬軟膏之藥物穿透研究
- 恩揚生物科技: 牛樟芝萃取物應用於治療乾癬及異位性皮膚炎之抗發炎
論文著作
The selected publications from total 339 articles
*, corresponding author
- Tsai, M.J., Lin, C.Y., Trousil, J., Sung, C.T., Lee, M.H., Fang, J.Y.*, Yang, S.C. (2023) Proteinase K/retinoic acid-loaded cationic liposomes as multifunctional anti-acne therapy to disorganize biofilm and regulate keratinocyte proliferation. Int. J. Nanomed., 18, 3879‒3896.
- Yang, S.C., Lin, C.F., Alshetaili, A., Aljuffalin, I.A., Chien, M.Y., Fang, J.Y.* (2023) Dual antibacterial and regenerative activities of platelet-rich plasma combined with β-lactam antibiotics are effective to treat MRSA-infected skin wound: the cell- and animal-based studies. Biomed. Pharmacother., 165, 115017.
- Huang, T.H., Chen, C.J., Lin, H.C.A., Chen, C.H., Fang, J.Y.* (2023) Self-nanoemulsifying drug delivery system-containing the poorly absorbed drug‒valsartan in post-bariatric surgery. Int. J. Nanomed., 18, 2647‒2658.
- Lin, C.Y., Yu, H.P., Chang, Y.T., Lin, Z.C., Alalaiwe, A., Hwang, T.L., Fang, J.Y.* (2023) Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils via Ly6 antigen for psoriasiform dermatitis alleviation. Biomater. Sci., 11, 873–893.
- Nirmal, G.R., Lin, Z.C., Lin, C.H., Sung, C.T., Liao, C.C., Fang, J.Y.* (2022) Polydopamine/IR820 nanoparticles as topical phototheranostics for inhibiting psoriasiform lesions through dual photothermal and photodynamic treatments. Biomater. Sci., 10, 6172–6189.
- Lee, W.R., Chou, W.L., Lin, Z.C., Sung, C.T., Lin, C.Y., Fang, J.Y.* (2022) Laser-assisted nanocarrier delivery to achieve cutaneous siRNA targeting for attenuating psoriasiform dermatitis. J. Control. Release, 347, 590–606.
- Tseng, C.H., Lin, C.F., Aljuffali, I.A., Huang, J.R., Yang, S.H., Fang, J.Y.* (2022) The effectiveness of synthetic methoxylated isoflavones in delivering to the skin and alleviating psoriasiform lesions via topical absorption. Int. J. Pharm., 617, 121629.
- Lee, W.R., Hsiao, C.Y., Chang, Z.Y., Wang, P.W., Aljuffali, I.A., Lin, J.Y., Fang, J.Y.* (2022) Cutaneous delivery of cosmeceutical peptides enhanced by picosecond- and nanosecond-domain Nd:YAG lasers with quick recovery of the skin barrier function: comparison with microsecond-domain ablative lasers. Pharmaceutics, 14, 450.
- Fang, J.Y., Huang, T.H., Chen, W.J., Aljuffali, I.A., Hsu, C.Y. (2022) Rhubarb hydroxyanthraquinones act as antiobesity agents to inhibit adipogenesis and enhance lipolysis. Biomed. Pharmacother., 146, 112497.
- Fang, J.Y., Chou, W.L., Lin, C.F., Sung, C.T., Alalaiwe, A., Yang, S.C. (2021) Facile biofilm penetration of cationic liposomes loaded with DNase I/proteinase K to eradicate Cutibacterium acnes biofilm for treating cutaneous and catheter infections. Int. J. Nanomed., 16, 8121–8138.
- Chuang, S.Y., Chen, C.Y., Yang, S.C., Alalaiwe, A., Lin, C.H., Fang, J.Y.* (2021) 2,4-Dimethoxy-6-methylbenzene-1,3-diol, a benzenoid from Antrodia cinnamomea, mitigates psoriasiform inflammation by suppressing MAPK/NF-κB phosphorylation and GDAP1L1/Drp1 translocation. Front. Immunol., 12, 664425.
- Nirmal, G.R., Lin, Z.C., Tsai, M.J., Yang, S.C., Alalaiwe, A., Fang, J.Y.* (2021) Photothermal treatment by PLGA-gold nanorod-isatin nanocomplexes under near-infrared irradiation for alleviating psoriasiform hyperproliferation. J. Control. Release, 333, 487–499.
- Lin, Z.C., Hwang, T.L., Huang, T.H., Tahara, K., Trousil, J., Fang, J.Y.* (2021) Monovalent antibody-conjugated lipid-polymer nanohybrids for active targeting to desmoglein 3 of keratinocytes to attenuate psoriasiform inflammation. Theranostics, 11, 4567–4584.
- Liao, C.C., Yu, H.P., Yang, S.C., Alalaiwe, A., Dai, Y.S., Liu, F.C., Fang, J.Y.* (2021) Multifunctional lipid-based nanocarriers with antibacterial and anti-inflammatory activities for treating MRSA bacteremia in mice. J. Nanobiotechnol., 19, 48.
- Elzoghby, A.O., Abdelmoneem, M.A., Hassanin, I.A., Abd Elwakil, M.M., Elnaggar, M.A., Mokhtar, S., Fang, J.Y., Elkhodairy, K.A. (2020) Lactoferrin, a multi-functional glycoprotein: Active therapeutic, drug nanocarrier and targeting ligand. Biomaterials, 263, 120355.
- Tang, K.W., Lin, Z.C., Wang, P.W., Alalaiwe, A., Tseng, C.H., Fang, J.Y.* (2020) Facile skin targeting of a thalidomide analog containing benzyl chloride moiety alleviates experimental psoriasis via the suppression of MAPK/NF-κB/AP-1 phosphorylation in keratinocytes. J. Dermatol. Sci., 99, 90–99.
- Alalaiwe, A., Lin, Y.K., Lin, C.H., Wang, P.W., Lin, J.Y., Fang, J.Y.* (2020) The absorption of polycyclic aromatic hydrocarbons into the skin to elicit cutaneous inflammation: the establishment of structure–permeation and in silico–in vitro–in vivo relationships. Chemosphere, 255, 126955.
- Yu, H.P., Liu, F.C., Lin, C.Y., Umoro, A., Trousil, J., Hwang, T.L., Fang, J.Y.* (2020) Suppression of neutrophilic inflammation can be modulated by the droplet size of anti-inflammatory nanoemulsions. Nanomedicine, 15, 773–791.
- Wu, C.Y.J., Chen, C.H., Lin, C.Y., Feng, L.Y., Lin, Y.C., Wei, K.C., Huang, C.Y., Fang, J.Y.*, Chen, P.Y. (2020) CCL5 of glioma-associated microglia/macrophages regulates glioma migration and invasion via calcium-dependent matrix metalloproteinase-2. Neuro-Oncology, 22, 253–266.
- Yu, H.P., Liu, F.C., Umoro, A., Lin, Z.C., Elzoghby, A.O., Hwang, T.L., Fang, J.Y.* (2020) Oleic acid-based nanosystems for mitigating acute respiratory distress syndrome in mice through neutrophil suppression: how the particulate size affects therapeutic efficiency. J. Nanobiotechnol., 18, 25.
- Lee, W.R., Lin, Y.K., Alalaiwe, A., Wang, P.W., Liu, P.Y., Fang, J.Y.* (2020) Fractional laser-mediated siRNA delivery for mitigating psoriasis-like lesions via IL-6 silencing. Mol. Ther.-Nucl. Acids, 19, 240–251.
- Chen, P.Y., Wu, C.Y.J., Fang, J.H., Chen, H.C., Feng, L.Y., Huang, C.Y., Wei, K.C., Fang, J.Y.*, Lin, C.Y. (2019) Functionl change of effector tumor-infiltrating CCR5+CD38+HLA-DR+CD8+ T cells in glioma microenvironment. Front. Immunol., 10, 2395.
- Weng, J.R., Huang, T.H., Lin, Z.C., Alalaiwe, A., Fang, J.Y.* (2019) Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-κB/AP-1 activation. Biomed. Pharmacother., 119, 109398.
- Hsiao, C.Y., Yang, S.C., Alalaiwe, A., Fang, J.Y.* (2019) Laser ablation and topical drug delivery: a review of recent advances. Expert Opin. Drug Deliv., 16, 937–952.
- Lin, C.Y., Hsu, C.Y., Elzoghby, A.O., Alalaiwe, A., Hwang, T.L., Fang, J.Y.* (2019) Oleic acid as the active agent and lipid matrix in cilomilast-loaded nanocarriers to assist PDE4 inhibition of activated neutrophils for mitigating psoriasis-like lesions. Acta Biomater., 90, 350–361.
- Fang, J.Y., Lin, C.H., Huang, T.H., Chuang, S.Y. (2019) In vivo rodent models of type 2 diabetes and their usefulness for evaluating flavonoid bioactivity. Nutrients, 11, 530.
- Lin, Z.C., Hsieh, P.W., Hwang, T.L., Chen, C.Y., Sung, C.T., Fang, J.Y.* (2018) Topical application of anthranilate derivatives ameliorates psoriatic inflammation in a mouse model by inhibiting keratinocyte-derived chemokine expression and neutrophil infiltration. FASEB J., 32, 6783–6795.
- Abdelmoneem, M.A., Mahmoud, M., Zaky, A., Helmy, M.W., Sallam, M., Fang, J.Y.*, Elkhodairy, K.A., Elzoghby, A.O. (2018) Dual-targeted casein micelles as green nanomedicine for synergistic phytotherapy of hepatocellular carcinoma. J. Control. Release, 287, 78–93.
- Elgohary, M.M., Helmy, M.W., Abdelfattah, E.Z.A., Ragab, D.M., Mortada, S.M., Fang, J.Y.*, Elzoghby, A.O. (2018) Targeting sialic acid residues on lung cancer cells by inhalable boronic acid-decorated albumin nanocomposites for combined chemo/herbal therapy. J. Control. Release, 285, 230–243.
- Chuang, S.Y., Lin, C.H., Sung, C.T., Fang, J.Y.* (2018) Murine models of psoriasis and their usefulness for drug discovery. Expert Opin. Drug Discov., 13, 551–562.
- Liu, F.C., Yu, H.P., Lin, C.Y., Elzoghby, A.O., Hwang, T.L., Fang, J.Y.* (2018) Use of cilomilast-loaded phosphatiosomes to suppress neutrophilic inflammation for attenuating acute lung injury: the effect of nanovesicular surface charge. J. Nanobiotechnol., 16, 35.
- Hsu, C.Y., Sung, C.T., Aljuffali, I.A., Chen, C.H., Hu, K.Y., Fang, J.Y.* (2018) Intravenous anti-MRSA phosphatiosomes mediate enhanced affinity to pulmonary surfactants for effective treatment of infectious pneumonia. Nanomed.-Nanotechnol. Biol. Med., 14, 215-225.
- Liu, K.S., Huang, T.H., Aljuffali, I.A., Chen, E.L., Wang, J.J., Fang, J.Y.* (2017) Exploring the structure-permeation relationship of topical tricyclic antidepressants used for skin analgesia. Int. J. Pharm., 523, 386–397.
- Hsieh, P.W., Hung, C.F., Lin, C.H., Huang, C.W., Fang, J.Y.* (2017) Anti-melasma codrug of retinoic acid assists cutaneous absorption with attenuated skin irritation. Eur. J. Pharm. Biopharm., 114, 154–163.
專利
- Fluorescent dye compositions and uses thereof, Chia-Yu Fang, Chih-Jen Wen, US9,855,346 B2, 美國, 2014/11/06-2034/11/06
- 使用2,4-二甲氧基-6-甲基苯-1,3-二醇來治療異位性皮膚炎，王東弘、方嘉佑、楊世駿、黃澤宏，I670055，中華民國 2019/9/1-2038/4/10
- 使用2,4-二甲氧基-6-甲基苯-1,3-二醇來防止和/或抑制葡萄球菌屬物種的生長以及生物膜形成，王東弘、方嘉佑、楊世駿、黃澤宏，I680756，中華民國 2020/1/1-2038/7/1
- 使用2,4-二甲氧基-6-甲基苯-1,3-二醇來預防和/或治療乾癬，王東弘、方嘉佑、楊世駿、莊士億、黃澤宏，I716940，中華民國 2021/1/21-2039/7/22
- 凝膠型防曬組成物，吳智元、楊世駿、王東弘、方嘉佑，I760745，中華民國 2022/4/11-2040/5/11
指導研究生論文
|
姓名 |
畢業年份 |
論 文 題 目 |
現職 |
|
G.R. Nirmal |
2022 |
Nanoparticles transduced near-infrared phototherapeutics for multimodal alleviation of psoriasiform lesions |
博後研究 (比利時 Ghent University) |
|
林承諭 |
2022 |
Targeting anti-inflammatory immunonanocarriers to human and murine neutrophils for psoriasiform dermatitis alleviation |
博後研究 (美國 Duke University) |
|
魏榯誸 |
2022 |
The effect of Chinese medicine compounds on the mitigation of atopic dermatitis |
研究助理 |
|
林姿瑋 |
2022 |
The development of conjugated linoleic acid-loaded nanocarriers for attenuating adipogenesis |
研究助理 |
|
簡旻瑜 |
2022 |
The combination of β-lactam antibiotics and platelet-rich plasma achieves synergistic bacterial eradication and skin regeneration in wound healing |
生技公司研發 |
|
李玫樺 |
2022 |
Multifunctional liposomes loaded with proteinase K and retinoic acid eradicate Cutibacterium acnes biofilm and reduce cutaneous proliferation for the aim of acne treatment |
生技公司研發 |
|
黃芷淇 |
2022 |
The effect of TiO2-containing mesoporous silica on the prevention of ultraviolet irradiation-induced skin aging and the adsorption of pollutants |
生技公司研發 |
|
黃昭容 |
2021 |
Cutaneous delivery of isoflavones for treating psoriasiform lesion |
研究助理 |
|
林芊郁 |
2021 |
Laser-assisted skin delivery of interleukin-6 siRNA-loaded nanocarriers for mitigating psoriasiform inflammation |
醫材公司研發 |
|
羅珮琦 |
2021 |
Laser-assisted skin delivery of retinoic acid-loaded polylactic acid/poly(lactic-co-glycolic acid) nanocarriers for treating photoaging |
研究助理 |
|
Thi My Huyen Nguyen |
2021 |
The anthraquinone compounds from rhubarb extract for mitigating psoriasiform inflammation |
生醫公司研發 |
|
陳韋彰 |
2021 |
The lipolysis activity of the compounds from rhubarb extract |
研究助理 |
|
李賢儒 |
2021 |
Bioactive effect of curcumin and its naturally occurring derivatives on 3T3-L1 adipocytes |
健康食品公司研發 |
|
林資展 |
2020 |
The investigation of novel anti-psoriatic agents: PDE4 inhibitors and active-targeting nanocarriers |
長庚科大研究員 |
|
吳智元 |
2020 |
Development of sunscreen-loaded mesoporous silica for protecting ultraviolet irradiation and air pollutant invasion |
藥廠 R&D |
|
鄭文婷 |
2020 |
Ablative lasers promote the skin delivery of platelet-rich plasma |
生技公司 R&D |
|
巫鈺茹 |
2020 |
Immune regulatory effect of tumor-infiltrating lymphocytes (TILs) and glioma-associated macrophages/microglia (GAMs) in glioma |
美國博後研究 |
|
連婉媜 |
2019 |
The establishment of structure-permeation relationship: flavanones and benzoxazinone derivative as the examples |
藥廠R&D |
|
Ani Umoro |
2019 |
The effect of lipid nanocarriers with different particle sizes for suppressing human neutrophil activation: Acute lung injury as a disease model |
印尼藥廠 |
|
楊雨青 |
2019 |
The drug-resistant pathogen inhibition by cationic nanoemulsions and furanoquinone derivatives |
研究助理 |
|
林婕瑀 |
2019 |
The relationship between percutaneous absorption and skin toxicity of polycyclic aromatic hydrocarbon compounds |
藥廠 R&D |
|
陳君漢 |
2018 |
Absorptive and therapeutic impacts of silymarin-loaded nanocarriers on post-gastric bypass surgery and obesity animals |
嘉義長庚醫師 |
|
劉珮瑩 |
2018 |
Fractional lasers for promoting the cutaneous absorption of macromolecules: diseased skins as the diffusion barriers |
研究助理 |
|
陳雅萍 |
2018 |
Cationic nanostructured lipid carriers as the vehicles of oxacillin for improving the inhibitory activity against drug-resistant bacteria |
藥廠 R&D |
|
陳恩立 |
2017 |
The establishment of structure-permeation relationship: tricyclic antidepressants and flavonoids as the examples |
研究助理 |
|
林承諭 |
2017 |
Development of cilomilast-loaded nanoformulations for inhibiting neutrophil activation: lipid nanoparticles and niosomes |
博後研究 |
|
黃昌尉 |
2016 |
Enhancement strategies of topical retinoic acid delivery: non-ablative fractional laser and co-drug |
藥廠研發管理 |
|
翁依涵 |
2016 |
New formulations and compounds for anti-MRSA therapy: malleable liposomes and natural products |
儀器公司研發 |
|
戴攸珊 |
2016 |
Passive and active targeting of silibinin-loaded nanocarriers for treating hepatic fibrosis |
生技公司研發 |
|
廖偉君 |
2016 |
Methylation and esterification of magnolol for ameliorating cutaneous targeting and therapeutic index by topical application |
生技公司研發管理 |
|
胡凱茵 |
2015 |
Design and development of nanocarriers for drug targeting to pulmonary tissue |
研究助理 |
|
高筱晴 |
2015 |
The cutaneous delivery of drugs via diseased skins: psoriasis and atopic dermatitis as examples |
醫美儀器產品專員 |
|
黃淳麟 |
2014 |
Development and investigation of multi-functional nanosystems for integrating bioimaging and drug delivery |
研究助理 |
|
張書豪 |
2014 |
Transdermal delivery systems of ketorolac ester prodrugs and hydroquinone-salicylic acid co-drugs |
財團法人藥技中心 |
|
施惠琪 |
2014 |
Establishment of skin permeability profiles for drug and sunscreen absorption via photoaging skin |
生技公司研發 |
|
洪宜筠 |
2013 |
Evaluation of skin response treated by bioactive and toxic compounds using different experimental platforms: magnolol/honokiol and phthalates as the permeants |
藥廠業務代表 |
|
黃雅慧 |
2013 |
Pharmacokinetics and bioimaging of nanostructured lipid carriers for anti-inflammation and angiography |
生技公司研發 |
|
沈逢鳴 |
2013 |
Preparation and evaluation of lipid nanoparticles for targeting to hair follicles |
藥廠產品經理 |
|
張媛婷 |
2013 |
The effect of cationic nanosystems in human neutrophils |
藥廠業務代表 |
|
李怡靜 |
2012 |
Influence of resurfacing laser on skin delivery of drugs: the risk of excessive drug absorption and enhancement of skin permeability |
生技公司企劃 |
|
陳浚責 |
2012 |
The co-drugs of conjugated hydroquinone/azelaic acid and hysroquinone/tranexamic acid for enhancing topical skin targeting and decreasing penetration through skin |
藥廠專案管理 |
|
袁丞音 |
2012 |
Transdermal drug delivery enhanced by fractional erbium:YAG laser |
美國進修博士學位 |
|
楊詩韻 |
2011 |
Evaluation of drug and sunscreen permeation via skin irradiated with UVA and UVB: comparisons of normal skin and chronologically aged skin |
生技公司品管分析師 |
|
古明娟 |
2011 |
Development and evaluation of drug delivery systems for apomorphine and its prodrugs |
藥廠研發 |
|
張惠雯 |
2010 |
Mechanistic studies of the skin delivery of lipid colloid systems with different oil/fatty ester ratios for both lipophilic and hydrophilic drugs |
藥廠產品經理 |
|
張力文 |
2010 |
Topical/transdermal delivery of natural antioxidants |
藥廠研發企劃 |
|
陳朝煌 |
2009 |
The physicochemical characteristics and pharmacokinetics of water-in-oil emulsions encapsulated with anti-bladder cancer drugs via intravesical route |
社區藥局藥師 |
|
蔡佳音 |
2009 |
Delivery of buprenorphine and its prodrugs formulated by lipid nanoparticles |
醫院藥師 |
|
紀政嫻 |
2009 |
The development and evaluation on drug delivery systems for anti-Parkinson’s drugs: nano-carriers for injection and transdermal delivery formulation |
分析檢驗公司講師 |
|
陳志杰 |
2009 |
Permeability and proteomicprofiles of heavy metals delivered by skin route |
粧品公司負責人 |
|
卓柔孜 |
2008 |
Enhancement of transdermal drug delivery by erbium:YAG Laser: peptides, vaccine, and anti-psoriatic Drug |
生技公司研發 |
|
蘇鈺涵 |
2008 |
The physicochemical characterization and drug delivery of lipid nanoparticles for topical and injectable dosage forms |
研究助理 |
|
黃梓柔 |
2008 |
Development and evaluation of resveratrol and soy Isoflavones in topical/transdermal delivery systems |
CRO 研究主管 |
|
葉智惠 |
2007 |
Design and characterization of drug delivery systems for narcotic prodrugs |
藥廠研發 |
|
花淑秋 |
2007 |
Development and investigation of nano-or submicron-sized vesicles for encapsulating cisplatin and camptothecin |
醫院藥師 |
|
胡濬文 |
2007 |
The thermo-sensitive hydrogels containing chitosan, hyaluronic acid and alginate as drug delivery systems |
生技公司研發主管 |
|
廖美惠 |
2006 |
Drug delivery and in vivo efficacy of resveratrol from nano/submicron encapsulated formulations |
藥廠業務代表 |
|
劉靜儒 |
2006 |
Transdermal delivery of drugs and genes enhanced by microdermabrasion and Er:YAG laser |
藥廠產品專員 |
|
黃妍菱 |
2005 |
The physicochemical characteristics and in vivo pharmacokinetics of tea catechins encapsulated with liposomes |
美國 |
|
翁玟雯 |
2005 |
Enhancing percutaneous absorption of theophylline and tea catechins by chemical and physical methods |
醫院藥師 |
|
王新元 |
2005 |
Hydrogels as drug carriers for both micro- and macromolecules |
藥師 |
|
張嘉駿 |
2004 |
Nano/submicron lipid emulsions composed of natural oils modulate drug and gene delivery |
中醫師 |
|
方逸萍 |
2004 |
Transdermal delivery of anti-cancer drugs promoted by physical enhancements |
高醫大副教授 |
|
邱顯智 |
2003 |
Evaluation of efficacy and safety on skin permeation enhancers: flurbiprofen and curcumin as model drugs |
馬來西亞生技公司主管 |
|
鄭曉菁 |
2003 |
Development of essential oils from Alpinia oxyphylla and Ocimum basilicum as novel skin permeation enhancers |
藥廠研發 |