化工與材料工程學系

研究領域

• 生物感測器之相關研究
• 網版印刷電極之修飾與快速檢測
• 載藥奈米微粒之基因控制釋放與眼睛皮膚傳遞
• 磁性奈米微粒之生化分離與基因傳遞

獲獎與榮譽

• 第一屆謝成源先生紀念科技獎(1998)
• 經濟部科專計畫成果優良獎(1998)

近年研究著作

For a complete listing of publications, please visit here. 

1. Pravanjan Malla, Chi-Hsien Liu*, Wei-Chi Wu, Pinpinut Kabinsing, Paiboon Sreearunothai. Synthesis and characterization of Au-decorated graphene oxide nanocomposite for magneto-electrochemical detection of SARS-CoV-2 nucleocapsid gene. Talanta, Volume 262, 124701. (2023), doi: 10.1016/j.talanta.2023.124701 , SCI, CHEMISTRY, ANALYTICAL 11/87.
2. Pinpinut Kabinsing, Pravanjan Malla, Chi-Hsien Liu*, Wei-Chi Wu, Paiboon Sreearunothai. Magnetic graphene oxide nanocomposite as dual-mode genosensor for ultrasensitive detection of oncogenic microRNA. Microchemical Journal, Volume 191, 108775. (2023), doi: 10.1016/j.microc.2023.108775 , SCI, CHEMISTRY, ANALYTICAL 17/87.
3. Liu, C.H.*, Lin, C.H., Chen, Y.J., Wu, W.C., Wang, C.C. Multifunctional magnetic nanocarriers for delivery of siRNA and shRNA plasmid to mammalian cells: Characterization, adsorption and release behaviors.. Colloid Surfaces B: Biointerfaces, 219 (11) 112861 (2022), doi:10.1016/j.colsurfb.2022.112861 , SCI, 11/76, BIOPHYSICS . 
4. Liu, C.H.*, Shih, P.Y., Lin, C.H., Chen, Y.J., Wu, W.C., Wang, C.C. Tetraethylenepentamine-Coated β Cyclodextrin Nanoparticles for Dual DNA and siRNA Delivery. Pharmaceutics 2022, 14, 921 (2022), doi: 10.3390/pharmaceutics14050921, IF 6.525 PHARMACOLOGY & PHARMACY 39/279
5. Liu, C.H.*, Lin, C.H., Chen, Y.J., Wu, W.C., Wang, C.C. Multifunctional magnetic nanocarriers for delivery of siRNA and shRNA plasmid to mammalian cells: Characterization, adsorption and release behaviors. Colloid Surfaces B: Biointerfaces, 219 (11) 112861. (2022), doi: 10.1016/j.colsurfb.2022.112861, IF 5.999, BIOPHYSICS 11/72
6. Malla, P., Liao, H.P., Liu, C.H.*, Wu, W.C., Sreearunothai, P., Voltammetric biosensor for coronavirus spike protein using magnetic bead and screen-printed electrode for point-of-care diagnostics, Microchimica Acta, 189(4), 168. (2022), doi: 10.1007/s00604-022-05288-4, IF 6.408 CHEMISTRY, ANALYTICAL 13/87
7. Chen, G. C., Liu, C. H.*, Wu, W. C. Electrochemical immunosensor for serum parathyroid hormone using voltammetric techniques and a portable simulator. Analytica Chimica Acta, 1143, 25, 84-92 (2021), doi: 10.1016/j.aca.2020.11.045, IF 6.56, CHEMISTRY, ANALYTICAL 8/98
8. Fan, Y. Y., Liu, C. H, Wu, A. L., Chen, H. C., Hsueh, Y. J.,Chen, K. J.,Lai, C. C.,Huang, C. Y., Wu, W. C.* MicroRNA-126 inhibits pathological retinal neovascularization via suppressing vascular endothelial growth factor expression in a rat model of retinopathy of prematurity, European Journal of Pharmacology, 900, 174035 (2021), doi: 10.1016/j.ejphar.2021.174035, IF 4.43 PHARMACOLOGY & PHARMACY 86/275  106- 2314-B-182A-040-MY3
9. Liu, C. H.*, Lee, G. W., Wu, W. C., Wang, C. C. Encapsulating curcumin in ethylene diamine-β-cyclodextrin nanoparticle improves topical cornea delivery. Colloids and Surfaces B: Biointerfaces 186, 110726, doi: 10.1016/j.colsurfb.2019.110726 (2020). IF 5.27, BIOPHYSICS 11/71.
10. Kumari, M., Liu, C. H.*, Wu, W. C. Oligochitosan modified albumin as plasmid DNA delivery vector: Endocytic trafficking, polyplex fate, in vivo compatibility. International Journal of Biological Macromolecules, 142, 492-502, doi: 10.1016/j.ijbiomac.2019.09.121 (2020). IF 6.95, CHEMISTRY, APPLIED 9/74 

專利

1. 劉繼賢, 賴宣余, 吳為吉, 純化血液中溶解纖維蛋白之酵素的方法2014(中華民國專利編號 460188)
2. 黃效民, 劉繼賢, 姚少凌, 朱一民, 謝祖柏, Optimizing culture medium for CD34+ hematopoietic cell expansion. 2014(USP 8,762,074)
3. 劉繼賢, 廖啟成, 2000 , 生產紅茶菇飲料之菌株及其用於發酵製備紅茶菇飲料之方法
   (日本國專利特許第3084348號) (中華民國專利編號385335)