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張家禎 / Chia-Chen Chang

職稱: 副教授

現職: 長庚大學醫技系專任教師

信箱: chang@mail.cgu.edu.tw

電話: 5086

學歷: 台灣大學醫學工程學研究所博士

專長領域: 生醫感測技術、生物分析化學

個人網頁: https://adamchangx.wixsite.com/nanosensing

研究方向及研究室特色(Lab & Research Interest)

功能性核酸之智慧檢測技術

我們致力於開發新型核酸奈米生物技術,利用核酸分子的智慧辨識、基因編輯以及類酵素催化等功能,發展可應用於醫學檢測與疾病診療等相關精準醫學領域的新型生物智慧檢測技術,並進行訊號放大策略的高敏度癌症標記物檢測方法的設計開發。

論文與著作(Publication)

最近五年所發表論文 

1.    C.C. Chang*,  C.P. Chen, T.H. Wu, C.H. Yang, C.W. Lin, C.Y. Chen. Gold Nanoparticle-Based Colorimetric Strategies for Chemical and Biological Sensing Applications. Nanomaterials  9, 6, 861 (2019)

2.    CC Chang*, G Wang, T Takarada, M Maeda. Target-recycling-amplified colorimetric detection of pollen allergen using non-cross-linking aggregation of DNA-modified gold nanoparticles. ACS Sensors 4, 363-369 (2019)

3.    CC Chang, CH Lee, TH Wu, CP Chen, CY Chen, CW Lin. Reversion of gold nanoparticle aggregates for the detection of Cu2+ and its application in immunoassays. Analyst 142 (24), 4684-4690 (2017).

4.    CC Chang*, G Wang, T Takarada, M Maeda. Iodine-mediated etching of triangular gold nanoplates for colorimetric sensing of copper ion and aptasensing of chloramphenicol. ACS Applied Materials & Interfaces 9 , 34518–34525 (2017).

5.    CC Chang, CP Chen, CY Chen, CW Lin. DNA base-stacking assay utilizing catalytic hairpin assembly-induced gold nanoparticle aggregation for colorimetric protein sensing. Chemical Communications 52, 4167-4170 (2016)

6.    CC Chang, CY Chen, TL Chuang, TH Wu, SC Wei, H Liao, CW Lin. Aptamer-based colorimetric detection of proteins using a branched DNA cascade amplification strategy and unmodified gold nanoparticles. Biosensors and Bioelectronics 78, 200-205 (2016)