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Chia-Rui Shen Ph.D.

Chia-Rui Shen Ph.D.

JobTitle： Professor

CurrentJob： Department and Graduate Institute of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University

E-mail： crshen@mail.cgu.edu.tw

Phone： 03-2118800 #5200

Education： Ph. D. in Immunology University of Bristol, UK

Expertise： Immuno-Regulation, Immunotherapy and Vaccine Development, Gene Therapy, Clinical Laboratory Science, Molecular Imaging

Employment Records

2023.08-present  Chair, IACUC committee, Chang Gung University, Taiwan.

2022.12-present Executive Supervisor, Taiwan Artificial Intelligence Advancement Association

2018.08-present Chair and Professor, Division of Biotechnology, Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Taiwan.

2018.08-present Professor, Master and PhD Program in Biotechnology Industry, College of Medicine, Chang Gung University, Taiwan.

2018.08-present  Member, IACUC committee, Chang Gung University, Taiwan.

2016.01-present  Research Fellow, Department of Ophthalmology, Linkuo Chang Gung Memorial Hospital, Taiwan.

2008.05-present  Council Member, Taiwan Society of Chitin and Chitosan

2012.11-2018.11 Council Member, Chinese Society of Immunology

2000.02-2018.07 Assistant/Associate Professor, Department of Medical Biotechnology and Laboratory Science, Graduate Institute of Biomedical Science, Master and PhD Program in Biotechnology Industry, Chang Gung University, Taiwan.

1998.09-2000.02 Academia Sinica Post-Doctoral Fellow, Institute of Biomedical Science, Academia Sinica, Taiwan.

1993.08-1994.07 Teaching Assistant, Department of Medical Technology, College of Medicine, National Cheng Kung University, Taiwan.


Education

1998      Ph.D.     Department of Pathology and Microbiology, Faculty of Medicine, University of Bristol, United Kingdom

1993      B.Sc.    Department of Medical Technology, College of Medicine, National Cheng Kung University, Taiwan.

Research Interests

Immuno-Regulation, Immunotherapy and Vaccine Development, Gene Therapy, Clinical Laboratory Science, Molecular Imaging.


Publications

  • Chen YS, Hwang CH, Liu CL, Chen HS, Wu ST, Lee MH, Shen CR*. Locally targeting the IL-17/ IL-17RA axis reduced tumor growth in a murine B16F10 melanoma model.  Hum Gene Ther. 2019 Mar; 30(3):273-285.
  • Barker NM, Li YX, Lee MM, Shen CR, Krause JA, Sun SS, Lu N, Connick WB, and McMillin DR. Synthesis, luminescence, and structure of a polymorphic polyfluorinated diiodoplatinum (II) diimine complex. Inorg Chem. 2019 Aug; 58(16):10716-10724.
  • Elakkat V, Chang CC, Chen JY, Fang YC, Shen CR*, Liu LK, Lu N. The first two examples of halogen bonding with a sigma hole-donating fluorine in the Csp3–F⋯Osp3 interaction from polyfluorinated trans-dihalo-palladium(II) di-substituted pyridine complexes. Chem Commun (Camb). 2019 Nov; 55(95):14259-14262. 
  • Juang JH, Wang JJ, Shen CR (equal to first), Chen CY, Kao CW, Chen CL, Lin SH, Wu ST, Li WC, Tsai ZT. Magnetic resonance imaging of transplanted porcine neonatal pancreatic cell clusters labeled with chitosan-coated superparamagnetic iron oxide nanoparticles in mice. Polymers 2021 Apr; 13(8):1238. 
  • Hsu LJ, Liu CL, Kuo ML, Shen CN, Shen CR*. An alternative cell therapy for cancers: induced pluripotent stem cell (iPSC)-derived natural killer cells. Biomedicines 2021; 9(10):1323.
  • Hwang YS, Kang EYC, Shen CR, Hong WH, Wu WC. Noncontact optical measurement of aqueous humor glucose levels and correlation with serum glucose levels in rabbit. Biosensors 2021; 11:387.
  • Juang JH, Shen CR (equal to first), Wang JJ, Wu ST, Lin SH, Chen CY, Kao CW, Chen CL, Tsai ZT, Wang YM. Exendin-4-conjugated manganese magnetism-engineered iron oxide nanoparticles as a potential magnetic resonance imaging contrast agent for tracking transplanted b-cells. Nanomaterials 2021; 11:3145.
  • Shen CR, Chen YS, Hwang YS, Chen HJ, Liu CL. Differential bicistronic gene translation mediated by the internal ribosome entry site element of encephalomyocarditis virus. Biomed J. 2021; 44(6):S54-S62.
  • Lo SM, Hwang YS, Liu CL, Shen CN, Hong WH, Yang WC, Lee MH, Shen CR*. Inhibiting TLR7 expression in the retinal pigment epithelium suppresses experimental autoimmune uveitis. Front Immunol. 2022; 12:736261.
  • Juang JH, Wang JJ, Shen CR (equal to first), Lin SH, Chen CY, Kao CW, Chen CL, Wu ST, Tsai ZT, Wang YM. Magnetic Resonance Imaging of Transplanted Porcine Neonatal Pancreatic Cell Clusters Labeled with Exendin-4-Conjugated Manganese Magnetism-Engineered Iron Oxide Nanoparticles. Nanomaterials 2022; 12(7):1222.