Tsong-Long Hwang Ph.D. / Members
JobTitle: Distinguished Professor
CurrentJob: College of Human Ecology, Chang Gung University of Science and Technology / Graduate Institute of Biomedical Sciences, Chang Gung University
E-mail: htl@mail.cgust.edu.tw
Phone: (03)211-8999#5510
Education: Ph.D., Institute of Pharmacology, National Taiwan University
Expertise: Inflammatory Pharmacology; Natural Medicine; Molecular Signaling; Drug Discovery; Cosmetic and Healthcare Product Development
Website: https://sites.google.com/view/fugmann-lab/home
2023-Present Vice President, Chang Gung University of Science and Technology
2017-Present Distinguished Professor, Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology
2015-Present Professor, Graduate Institute of Health Industry Technology, Chang Gung University of Science and Technology
2024-Present Adjunct Professor, Department of Traditional Chinese Medicine, National Yang Ming Chiao Tung University
2023-Present Adjunct Professor, Department of Traditional Chinese Medicine, Chang Gung University
2018-Present Adjunct Professor, Department of Chemical Engineering, Ming Chi University of Technology
2016-Present Adjunct Researcher, Department of Anesthesiology, Chang Gung Memorial Hospital
2015-2023 Dean, College of Human Ecology, Chang Gung University of Science and Technology
2010-2023 Professor, Master Program in Natural Products, Department of Traditional Chinese Medicine, Chang Gung University
2013-2023 Professor, Division of Natural Products, Graduate Institute of Biomedical Sciences, Chang Gung University
2015-2023 Dean, College of Human Ecology, Chang Gung University of Science and Technology (On Secondment)
2010-2023 Professor, Master Program in Natural Products, Department of Traditional Chinese Medicine, Chang Gung University
2013-2023 Professor, Division of Natural Products, Graduate Institute of Biomedical Sciences, Chang Gung University
2010-2015 Associate Chair, Department of Traditional Chinese Medicine, Chang Gung University
2013-2015 Director, Division of Natural Products, Graduate Institute of Biomedical Sciences, Chang Gung University
2009-2010 Professor, Graduate Institute of Natural Products, Chang Gung University
2005-2009 Associate Professor, Graduate Institute of Natural Products, Chang Gung University
2000-2005 Assistant Professor, Graduate Institute of Natural Products, Chang Gung University
Education
1996-2000 PhD, Graduate Institute of Pharmacology, National Taiwan University1991-1993 MS, Graduate Institute of Medicine, Kaohsiung Medical University
1987-1991 BS, Department of Pharmacy, Kaohsiung Medical University
Publications
1. Chen SH, Chen CH, Lin HC, Yeh SA, Hwang TL*, Chen PJ*. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis. J Adv Res. 2025 May 2;8(6):1591-1609.2. Chiang CC, Cheng WJ, Dela Cruz JRMS, Raviraj T, Wu NL*, Korinek M*, Hwang TL*. Neutrophils in Atopic Dermatitis. Clin Rev Allergy Immunol. 2024 Dec;67(1-3):21-39.
3. Chen PJ, Chen SH, Chen YL, Wang YH, Lin CY, Chen CH, Tsai YF, Hwang TL*. Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome. J Adv Res. 2024 Aug:62:229-243.
4. Lin CJ, Hwang TL*, Wang RYL, Nain A, Shih RH, Chang L*, Lin HJ, Harroun SG, Chang HT, Huang CC*. Augmenting Neutrophil Extracellular Traps with Carbonized Polymer Dots: A Potential Treatment for Bacterial Sepsis. Small. 2024 Jan 26:e2307210.
5. Chen PJ, Tseng HH, Wang YH, Fang SY, Chen SH, Chen CH, Tsai SC, Chang YC, Tsai YF, Hwang TL*. Palbociclib blocks neutrophilic phosphatidylinositol 3-kinase activity to alleviate psoriasiform dermatitis. Br J Pharmacol. 2023 Aug;180(16):2172-2188.
6. Yang SC, Wang YH, Ho CM, Tsai YF, Sung PJ, Lin TE, Hwang TL*. Targeting formyl peptide receptor 1 by anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome. Br J Pharmacol. 2023 Aug;180(16):2120-2139.
7. Kao TI, Chen PJ, Wang YH, Tseng HH, Chang SH, Wu TS, Yang SH, Lee YT, Hwang TL*. Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity. Br J Pharmacol. 2021 Oct;178(20):4069-4084.
8. Tsai YF, Chen CY, Lin IW, Leu YL, Yang SC, Syu YT, Chen PJ, Hwang TL*. Imperatorin Alleviates Psoriasiform Dermatitis by Blocking Neutrophil Respiratory Burst, Adhesion, and Chemotaxis Through Selective Phosphodiesterase 4 Inhibition. Antioxid Redox Signal. 2021 Oct 10;35(11):885-903.
9. Wu YH, Kuo CF, Hsieh AH, Hsieh HL, Chan YF, Hwang TL*. Upregulation of miR-210–5p impairs dead cell clearance by macrophages through the inhibition of Sp1-and HSCARG-dependent NADPH oxidase pathway. Free Radic Biol Med. 2021 Jun 29;172:441-450.
10. Lu YJ, Wang YH, Sahu RS, Chen JP, Dash BS, Chung PJ, Yang HW, Chuang EY*, Hwang TL*. Mechanism of Nanoformulated Graphene Oxide-Mediated Human Neutrophil Activation. ACS Appl Mater Interfaces. 2020 Sep 9;12(36):40141-40152.
11. Chen PJ, Ko IL, Lee CL, Hu HC, Chang FR, Wu YC, Leu YL, Wu CC, Lin CY, Pan CY, Tsai YF, Hwang TL*. Targeting allosteric site of AKT by 5,7-dimethoxy-1,4-phenanthrenequinone suppresses neutrophilic inflammation. EBioMedicine. 2019 Feb;40:528-540.
12. Liu FC, Yu HP, Chen PJ, Yang HW, Chang SH, Tzeng CC, Cheng WJ, Chen YR, Chen YL*, Hwang TL*. A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice. Redox Biol. 2019 Jul 10;26:101273.