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Chia-Yu Yang Ph.D.

Chia-Yu Yang Ph.D.

JobTitle： Associate Professor

CurrentJob： Graduate Institute of Biomedical Sciences / Division of Microbiology and Immunology

E-mail： chiayu-yang@mail.cgu.edu.tw

Phone： 03-2118800 #3527 or 5370

Education： National Defense Medical Center/Taiwan

Expertise： Clinical Immunomics

Employment Records

2021/08－Present   Associate Professor, Dept. of Microbiology & Immunology, Chang Gung University, Taiwan.
2016/08－2021/07   Assistant Professor, Dept. of Microbiology & Immunology, Chang Gung University, Taiwan. 
2014/03－2016/07   Assistant Research Fellow, Molecular Medicine Research Center, Chang Gung University, Taiwan.
2010/02－2014/01   Postdoctoral Fellow, Immunology Research Center, National Health Research Institutes, Taiwan.
2009/02－2009/12    Postdoctoral Fellow, Institute of Molecular Biology, Academia Sinica, Taiwan.
2001/07－2002/08    Research Assistant, Institute of Molecular Biology, Academia Sinica, Taiwan. 

Education

2002/9-2009/2   Ph.D., Graduate Institute of Life Sciences, National Defense Medical Center, Taiwan.
1999/9-2001/7   M.S., Dept. of Public Health, National Yang-Ming University, Taiwan. 
1995/9-1999/6   B.S., Dept. of Medical Biotechnology and Laboratory Science, Chang Gung University, Taiwan. 

Research Interests

Molecular regulatory mechanisms of dual-specificity phosphatases (DUSPs) in immune cells and immune responses
Investigation of oncogenic mechanisms and development of targeted therapeutic strategies for oral cancer
Genomic analysis of immune repertoire and microbiome

[臨床免疫體學實驗室]
Clinical Immunomics Laboratory

Publications

  • Wang LJ, Tsai CS, Chou WJ, Kuo HC, Huang YH, Lee SY, Dai HY, Yang CY, Li CJ, Yeh YT. Wang. Add-On Bifidobacterium Bifidum Supplement in Children with Attention-Deficit/Hyperactivity Disorder: A 12-Week Randomized DoubleBlind Placebo-Controlled Clinical Trial. Nutrients. 2024, 6(14):2260.
  • Lee SY, Li SC, Yang CY, Kuo HC, Chou WJ, Wang LJ. Gut leakage markers and cognitive functions in patients with Attention-Deficit/Hyperactivity Disorder. Children, 2023, 10:513.
  • Wang LJ, Li SC, Yeh YM, Lee SY, HC Kuo, Yang CY*. Gut mycobiome dysbiosis and its impact on intestinal permeability in attention deficit/hyperactivity disorder. Journal of Child Psychology and Psychiatry, 2023, doi:10.1111/jcpp.13779.
  • Wang LJ, Yang CY, Kuo HC, Chou WJ, Tsai CS, Lee SY. Effect of Bifidobacterium bifidum on Clinical Characteristics and Gut Microbiota in Attention-Deficit/Hyperactivity Disorder. Journal of Personalized Medicine, 2022, 12:227.
  • Wang LJ, Li SC, Li SW, Kuo HC, Lee SY, Huang LH, Chin CY, Yang CY*. Gut microbiota and plasma cytokine levels in patients with attention deficit/hyperactivity disorder. Translational Psychiatry, 2022, 12:76.
  • Chen YT, Hsu HC, Lee YS, Liu H, Tan CM, Chin CY, Chang YF, Yang CY*. Longitudinal High-Throughput Sequencing of the T-Cell Receptor Repertoire Reveals Dynamic Change and Prognostic Significance of Peripheral Blood TCR Diversity in Metastatic Colorectal Cancer During Chemotherapy. Frontiers in Immunology, 2022, 12:743448.
  • Yen WC, Chang IYF, Chang KP, Ouyang CN, Liu CR, Tsai TL, Zhang YC, Wang CI, Wang YH, Yu AL, Liu H, Wu CC, Chang YS, Yu JS, Yang CY*. Genomic and Molecular Signatures of Successful Patient-Derived Xenografts for Oral Cavity Squamous Cell Carcinoma. Frontiers in Oncology, 2022, 12:792297.
  • Hsu PY, Chen JL,Kuo SL, Wang WL,Jan FW,Yang SH, Yang CY*. San-Zhong Kui-Jian-Tang Exerts Antitumor Effects Associated With Decreased Cell Proliferation and Metastasis by Targeting ERK and the Epithelial–Mesenchymal Transition Pathway in Oral Cavity Squamous Cell Carcinoma. Integrative Cancer Therapies, 2022, 21: 15347354221134921.
  • Lai CH, Lin TL, Huang MZ, Li SW, Wu HY, Chiu YF, Yang CY, Chiu CH, Lai HC. Gut Commensal Parabacteroides goldsteinii MTS01 Alters Gut Microbiota Composition and Reduces Cholesterol to Mitigate Helicobacter pylori-Induced Pathogenesis. Frontiers in Immunology, 2022, 13:916848.
  • Yang CK, Hsu HC, Liu YH, Tsai WS, Ma CP, Chen YT, Tan CM, Lai YY, Chang YF, Yang C, Yang CY, Yu JS, Liu H. EV-miRome-wide profiling uncovers miR-320c for detecting metastatic colorectal cancer and monitoring the therapeutic response. Cellular Oncology, 2022, 45:621-638.
  • Yang CY, Kuo YH, Chen M, Wang CL, Shih LJ, Liu YC, Hsueh PC, Lai YH, Chu CM, Wu CC, Wu KA. Pleural cytokines MIF and MIP-3α as novel biomarkers for complicated parapneumonic effusions and empyema. Scientific Reports, 2021 Jan: 11: 1763.
  • Tseng MH, Fan WJ, Liu H, Yang CY, Ding JJ, Lee HJ, Huang SM, Lin SH, Huang JL. Complement factor I mutation may contribute to development of thrombotic microangiopathy in lupus nephritis. Frontiers in Medicine, 2021 Feb: 7: 621609.
  • Yang CY, Li SW, Chih CY, CW Hsu, Lee CC, Yeh YM, Wu KA. Association of exacerbation phenotype with the sputum microbiome in chronic obstructive pulmonary disease patients during the clinically stable state. Journal of Translational Medicine, 2021 Mar: 19:121.
  • Tsai WS, Hung WS, Wang TM, Liu H, Yang CY, Wu SM, Hsu HL, Hsiao YC, Tsai HJ, Tseng CP. Circulating tumor cell enumeration for improved screening and disease detection of patients with colorectal cancer. Biomedical Journal, 2021, 44:S190-S200.
  • Wu SM, Dr. Tsai WS, Chiang SF, Lai YH, Ma CP, Wang JH, Ms. Lin JR, Lu PS, Yang CY, Liu H, Tan BC. (2020). Comprehensive transcriptome profiling of Taiwanese colorectal cancer implicates an ethnic basis for pathogenesis. Scientific Reports. 10:4526.