施瀚博 / Han-Po Shih
職稱： 助理教授
現職： 長庚大學免疫轉譯醫學研究所 專任教師
電話： 03-211-8800#5542
學歷： 長庚大學臨床醫學研究所博士
專長領域： 癌症免疫治療，開發具有強效抗腫瘤活性的治療性γδT細胞、白斑症免疫治療
學歷
2022 長庚大學臨床醫學研究所博士
2010 臺灣大學生化分生所碩士
2007 臺灣大學植物病理與微生物學系學士
經歷
2025-迄今 長庚大學免疫與轉譯醫學研究所專任教師
2024-2025 長庚大學分子與臨床免疫中心助理研究員
2023-2024 長庚大學分子與臨床免疫中心博士後研究員
榮譽
2024 台北生技獎 技轉合作獎
2023 沈水德翁學術論文獎
2021 Scholarship, Séjour scientifique de haut niveau (SSHN) Institut Pasteur, Paris, France
2021 Poster Award, 2021 Joint Annual Conference of Taiwan Allergy and Immunology, Kaohsiung, Taiwan
2020 FISS Travel Award, The 2020 Annual Meeting of Chinese Society of Immunology, Taipei, Taiwan
2020 Fellowship, The 9th Singapore Immunology Network/Immunology Frontier Research Center (NIF) Winter School on Advanced Immunology, Osaka, Japan
2019 Award for Excellent Contributions in Technology Transfer, Ministry of Science and Technology, Taipei, Taiwan
2019 Poster Award, 2019 Formosa Immunology Spring School & Symposium (FISS), Taoyuan, Taiwan
2018 Oral Award, The 9th Annual Symposium of Graduate Institute of Clinical Medicine in Taiwan Precision Medicine 2018, Taoyuan, Taiwan
2017 Scholar Exchange Program (Program Orchid),
Institut Pasteur, Paris, France
論文（選錄）
1. Ng CY, Chan YP, Chiu YC, Shih HP, Lin YN, Chung PH, Huang JY, Chen HK, Chung WH, Ku CL. Targeting the elevated IFN-γ in vitiligo patients by human anti-IFN-γ monoclonal antibody hampers direct cytotoxicity in melanocyte. J Dermatol Sci. 2023 110(3):78-88.
2. Wang SY, Lo YF, Shih HP, Ho MW, Yeh CF, Peng JJ, Ting HT, Lin KH, Huang WC, Chen YC, Chiu YH, Hsu CW, Tseng YT, Wang LS, Lei WY, Lin Cy, Aoh Y, Chou CH, Wu TY, Ding JY, Lo CC, Lin YN, Tu KH, Lei WT, Kuo CY, Chi CY, Ku CL. Cryptococcus gatti Infection as the Major Clinical Manifestation in Patients with Autoantibodies Against Granulocyte-Macrophage Colony-Stimulating Factor. J Clin Immunol. 2022 42(8):1730-1741.
3. Shih HP*, Ding JY, Bellón JS, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response. J Exp Med. 2022 219(9):e20212126.
4. Shih HP*, Ding JY, Yeh CF, Chi CY, Ku CL. Anti-interferon-γ autoantibody-associated immunodeficiency. Curr Opin Immunol. 2021 72:206-214.
5. Guo J, Ning XQ, Ding JY, Zheng YQ, Shi NN, Wu FY, Lin YK, Shih HP, Ying HT, Liang G, Lu XC, Kong JL, Wang K, Lu BY, Fu YJ, Hu R, Li TM, Pan KS, Li XY, Hung CY, Lo YF, Chang IYF, Yeh CF, Yu KH, Tsai YH, Ku CL, Cao CW. Anti-IFN-γ autoantibodies underlie disseminated Talaromyces marneffei infections. J Exp Med. 2020 217(12): e20190502
6. Kuo CY, Wang SY, Shih HP, Tu KH, Huang WC, Ding JY, Lin CH, Yeh CF, Ho MW, Chang SC, He CY, Chen HK, Ho CH, Lee CH, Chi CY, Ku CL. Disseminated Crytococcosis Due to Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibodies in the Absence of Pulmonary Alveolar Proteinosis. J Clin Immunol. 2017 37 (2):143-152.
7. Lin CH, Chi CY, Shih HP, Ding JY, Lo CC, Wang SY, Kuo CY, Yeh CF, Liu SH, Tu KH, Ho MW, Lin PC, Chen HK, Ho CH, Lee CH, Lai HC, Ku CL. Identification of a major epitope by anti-interferon-γ autoantibodies in patients with mycobacterial disease. Nat Med. 2016 22 (9):994-1001.