長庚大學

經歷

學歷

研究方向

研究論文(選錄)

• Yeh JA, Huang HK, Chou AL, Lin HJ, Feng CL, Kuo CJ, Lai CH*. Helicobacter pylori eradication with high-dose proton pump inhibitor-amoxicillin dual therapy: A systematic review and meta-analysis. Int J Antimicrob Agents. 2024;63(6):107159.
• Ma J†, Chiu YF†, Kao CC, Chuang CN, Chen CY, Lai CH†, Kuo ML*. Fine particulate matter manipulates immune response to exacerbate microbial pathogenesis in the respiratory tract. Eur Respir Rev. 2024 Sep 4;33(173):230259. (†equal contribution)
• Chang YF, Huang YP, Chou CH, Ho MW, Lin HJ, Chen CY, Wu HY, Lai YR, Lee YH, Chiu CH, Lai CH*. RAGE participates in the intracellular transport of Campylobacter jejuni cytolethal distending toxin. J Microbiol Immunol Infect. 2024:S1684-1182(24)00118-X. 
• Ho SM†, Tsai WH†, Lai CH†, Chiang MH, Lee WP, Wu HY, Bai PY, Wu T, Wu CL*. Probiotic Lactobacillus spp. improves Drosophila memory by increasing lactate dehydrogenase levels in the brain mushroom body neurons. Gut Microbes. 2024;16(1):2316533. (†equal contribution)
• Huang HL, Lai CH, Tsai WH, Chen KW, Peng SL, Lin JH, Lin YH. Nanoparticle-enhanced postbiotics: Revolutionizing cancer therapy through effective delivery. Life Sci. 2024;337:122379.
• Kuo CJ, Bui NN, Ke JN, Lin CY, Lin WR, Chang ML, Wu HY, Huang MZ, Chiu CH, Chiu CT, Lai CH*. Molecular characterization of rifabutin-resistance in refractory Helicobacter pylori infection in Taiwan. Int J Infect Dis. 2023;138:25-28. 
• Wu HY, Kuo CJ, Chou CH, Ho MW, Chen CL, Hsu TS, Chen YC, Chiang-Ni C, Chen YM, Chiu CH, Lai CH*. Clostridium innocuum, an emerging pathogen that induces lipid raft-mediated cytotoxicity. Virulence. 2023;14(1):2265048.
• Bui NN, Li CY, Wang LY, Chen YA, Kao WH, Chou LF, Hsieh JT, Lin H, Lai CH*. Clostridium scindens metabolites trigger prostate cancer progression through androgen receptor signaling. J Microbiol Immunol Infect. 2023;56(2):246-256.
• Kuo CJ, Ke JN, Kuo T, Lin CY, Hsieh SY, Chiu YF, Wu HY, Huang MZ, Bui NN, Chiu CH, Chiu CT, Lai CH*. Multiple amino acid substitutions in penicillin-binding protein-1A confer amoxicillin resistance in refractory Helicobacter pylori infection. J Microbiol Immunol Infect. 2023;56(1):40-47.
• Lai CH*, Lin TL, Huang MZ, Li SW, Wu HY, Chiu YF, Yang CY, Chiu CH, Lai HC*. Gut commensal P. goldsteinii MTS01 alters gut microbiota composition and reduces cholesterol to mitigate Helicobacter pylori-induced pathogenesis. Front Immunol. 2022;13 (916848):1-13.
• Chou LF, Chen TW, Yang HY, Tian YC, Chang MY, Hung CC, Lai CH, Hsu SH, Tsai CY, Ko YC, Lian JH, Yang CW. Implication of the IL-10-expression signature in the pathogenicity of Leptospira-infected macrophages. Microbiol Spectr. 2022;10(3):e0259521.
• Lo UG, Chen YA, Cen J, Deng S, Luo J, Zhau H, Ho L, Lai CH, Mu P, Chung LWK, Hsieh JT*. The driver role of JAK-STAT signaling in cancer stemness capabilities leading to new therapeutic strategies for therapy- and castration-resistant prostate cancer. Clin Transl Med. 2022;12(8):e978.
• Chiang MH, Ho SM, Wu HY, Lin YC, Tsai WH, Wu T, Lai CH*, Wu CL*. Drosophila model for studying gut microbiota in behaviors and neurodegenerative diseases. Biomedicines. 2022;10(3):596.
• Lee CF, Chen YA, Hernandez E, Pong RC, Ma S, Hofstad M, Kapur P, Zhau H, Chung LW, Lai CH, Lin H, Lee MS, Raj GV, Hsieh JT*. The central role of Sphingosine kinase 1 in the development of neuroendocrine prostate cancer (NEPC): A new targeted therapy of NEPC. Clin Transl Med. 2022;12(2):e695.
• Hsu CY, Yeh JY, Chen CY, Wu HY, Chiang MH, Wu CL, Lin HJ, Chiu CH, Lai CH*. Helicobacter pylori cholesterol-α-glucosyltransferase manipulates cholesterol for bacterial adherence to gastric epithelial cells. Virulence. 2021;12(1): 2341-2351.