Institute for Radiological Research

I-Chun Cho PhD TEL：(03)2118800 ext. 3015 Email：iccho@mail.cgu.edu.tw WEB：https://www.researchgate.net/profile/I-Cho ORCID iD：https://orcid.org/0000-0002-8000-5332 現職 Assistant Research Fellow 學歷 Ph.D. of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Taiwan M.S. of Medical Image, Yuan Pei University of Technology, Taiwan B.E. of Biomedical Engineering, Chung-Yuan Christian University, Taiwan 經歷 2022/08 -  Present Assistant Researcher, Institute for Radiological Research, Chang Gung University 2019/07 – 2022/07 Medical Physicist, Proton Center of Kaohsiung Chang Gung Memorial Hospital 2018/10 – 2019/07 Associate Researcher, National Kaohsiung University of Science and Technology 2018/04 – 2018/10 Youth Visiting Researcher, Institute of Modern Physics, Chinese Academy of Sciences 2014/01 – 2018/03 Postdoctoral Fellow, Department of Medical Imaging and Radiological Sciences, Chung Gung University 研究領域 Charged particle therapy, Dosimetry, Microdosimetry, Radiation measurement, Monte Carlo simulation 近五年五篇代表著作 J. H. Lan, C. S. Shieh, C. H. Liu, I. C. Cho, I. H. Tsai, L. C. Chen, P. J. Chao, H. F. Lee, Y. J. Huang, and T. F. Lee, “Plan Quality and Secondary Cancer Risk Assessment in Patients with Benign Intracranial Lesions after Radiosurgery using the CyberKnife M6 Robotic Radiosurgery System,” Scientific Reports 9 (2019) pp.9953 I.C. Cho, H. Niu, Y.C. Liu, F.H. Chen, “The application of vertical charged particle irradiation platform in GBM cancer stem cells study”, Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 441 (2019) 102-107. T. C. Chao, I. C. Cho, C. H. Hsing, C. J. Tung, “Measurements of microdosimetric spectra for particle therapy”, Basic & Clinical Pharmacology & Toxicology 124 S3 (2019), 193-194. I.C. Cho, F.H. Chen, T.C. Chao, C.J. Tung, “A Monte Carlo study of bone-tissue interface microdosimeter”, Applied Radiation and Isotopes, 140 (2018) 193-200.  C.H. Hsing, I.C. Cho, T.C. Chao, J.H. Hong, C.J. Tung, “GNP enhanced responses in microdosimetric spectra for 192Ir source”, Radiation Measurements, 118 (2018) 67-71. 歷年計畫主持人研究計畫

Ching-Yi Hsieh PhD TEL：(03)3281200 ext. 7251 Email：chsieh2016@mail.cgu.edu.tw WEB：Under construction 現職 Assistant Research Fellow 學歷 Wayne State University, Michigan, USA 經歷 2016/02 ~ 2016/07 林口長庚醫院 博士後研究員 研究領域 Magnetic Resonance Imaging、Hyperpolarized 13C Magnetic Resonance、Magnetic Susceptibility 近五年五篇代表著作 Yenpo Lin, Ching-Yi Hsieh, Yen-Ling Huang, Kueian Chen, Yu-Ting Huang, Ren-Chin Wu, Huei-Jean Huang, Hung-Hsueh Chou, Angel Chao, Chyong-Huey Lai and Gigin Lin (2021, Oct). Magnetic Resonance Spectroscopy for Risk Stratification of Sonographically Indeterminate Ovarian Neoplasms:Preliminary Study. diagnostics, 2021, 11, 1847. (SCIE). Ying-Chieh Lai, Ching-Yi Hsieh, Kuan-Ying Lu, Cheng-Hsuan Sung, Hung-Yao Ho, Mei-Ling Cheng,Albert P. Chen, Shu-Hang Ng, Fang-Hsin Chen, and Gigin Lin (2021, Aug). Monitoring Early Glycolytic Flux Alterations Following Radiotherapy in Cancer and Immune Cells: Hyperpolarized Carbon-13 Magnetic Resonance Imaging Study. metabolites, 11, 518. (Scopus). MOST 107-2221-E-182-023. He Xie, Y.-C.N. Cheng, P. Kokeny, S. Liu, C.-Y. Hsieh, E. M. Haacke, M. P. Arachchige, G. Lawes, A quantitative study and additional frequency shift of three common materials in MRI, Magn. Reson. Med.,76(4), pp. 1263-1269. 歷年計畫主持人研究計畫

林中英 博士 電話、分機：(03)2118800 ext. 3865 Email：Winwood5782@gmail.com 實驗室網頁：https://www1.cgmh.org.tw/intr/intr2/c31570/index.html 現職 長庚大學放射醫學研究院 副研究員 學歷 國立臺灣大學 醫學工程研究所 經歷 2014/08 ~ 2017/08 長庚大學放射醫學研究院 助理研究員 2014/08 ~ 2017/08 長庚醫院臨床毒物中心 助理研究員 2013/10 ~ 2014/08 長庚醫院神經外科暨臨床毒物科 博士後研究員 2012/07 ~ 2013/09 Brigham Young University/University of Utah Visiting Scholar 研究領域 Medical Ultrasound、CNS diseases、Drug transportation、Toxicology 近五年五篇代表著作 請參閱：https://arspb.nstc.gov.tw/NSCWebFront/modules/talentSearch/talentSearch.do?action=initRsm05&rsNo=4062f23c3ae3416bbbef7d58d77e6462&LANG=chi 歷年計畫主持人研究計畫 請參閱：https://arspb.nstc.gov.tw/NSCWebFront/modules/talentSearch/talentSearch.do?action=initRsm17new&rsNo=4062f23c3ae3416bbbef7d58d77e6462&LANG=chi

Chun-Chia Cheng PhD TEL：(03)2118800 ext. 3864 Email：cccheng.biocompare@gmail.com WEB：https://www.researchgate.net/profile/Chun-Chia-Cheng 現職 Assistant Research Fellow 學歷 Ph.D. Degree: Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taiwan. 經歷 2015/12 ~ 2016/07 Postdoctoral Fellow in Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan. 2016/09 ~ 2018/09 Assistant Researcher in Hematology and Oncology, Mackay Memorial Hospital, Taipei, Taiwan. 2018/10 ~ 2019/07 Postdoctoral Fellow in Institute of Molecular and Genomic Medicine, National Health Research Institute, Taiwan. 研究領域 Radiobiology, Cancer Biology, Cancer Immunology, Biotechnology 近五年五篇代表著作 Chun-Chia Cheng, Yi-Fang Chang, Ai-Sheng Ho, Zong-Lin Sie, Jungshan Chang, Cheng-Liang Peng, and Chun-Chao Chang. Irradiation mediates IFNα and CXCL9 expression in non-small cell lung cancer to stimulate CD8+ T cells activity and migration toward tumors. Biomedicines. 2021, 9, 1349. (SCI/IF: 6.08) Chun-I Wang, Yi-Fang Chang, Zong-Lin Sie, Ai-Sheng Ho, Jungshan Chang, Cheng-Liang Peng and Chun-Chia Cheng*. Irradiation Suppresses IFNγ-Mediated PD-L1 and MCL1 Expression in EGFR-Positive Lung Cancer to Augment CD8+ T Cells Cytotoxicity. Cells. 2021, 10(10), 2515. *Corresponding author. (SCI/IF: 6.6) Chun-Chia Cheng, Hsin-Chi Lin, Ya-Wen Chiang, Jungshan Chang, Zong-Lin Sie, Bi-Ling Yang, Ken-Hong Lim, MD, Cheng-Liang Peng, Ai-Sheng Ho, Yi-Fang Chang. Nicotine exhausts CD8+ T cells against tumor cells through increasing miR-629-5p to repress IL2RB-mediated granzyme B expression. Cancer Immunology, Immunotherapy. 2020, 70(5):1351-1364. (SCI/IF: 6.968) Chun-Chia Cheng, Bi-Ling Yang, Wen-Chao Chen, Ai-Sheng Ho, Zong-Lin Sie, Hsin-Chi Lin and Chun-Chao Chang. STAT3 Mediated miR-30a-5p Inhibition Enhances Proliferation and Inhibits Apoptosis in Colorectal Cancer Cells. International Journal of Molecular Sciences. 2020, 21:7315. (SCI/IF: 5.923) Chun-Chia Cheng, Wan-Yu Yang, Ming-Chen Hsiao, Kuan-Hao Lin, Hao-Wei Lee, and Chiou-Hwa Yuh. Transcriptomically Revealed Oligo-Fucoidan Enhances the Immune System and Protects Hepatocytes via the ASGPR/STAT3/HNF4A Axis. Biomolecules. 2020, 10:898. (SCI/IF: 4.879) 歷年計畫主持人研究計畫 2021 ~ 2022 Grant from the Ministry of Science and Technology of Taiwan. (MOST 110-2314-B-182-031), Study for investigating the mechanism of cancer cells on exhausting immunological cells and detected by a nuclear imaging platform (2/2) 2020 ~ 2021 Grant from the Ministry of Science and Technology of Taiwan. (MOST 109-2314-B-182-011), Study for investigating the mechanism of cancer cells on exhausting immunological cells and detected by a nuclear imaging platform (1/2)

Jan, Meei-Ling PhD TEL：(03)2118800 ext. 3863 Email：mljan@mail.cgu.edu.tw WEB：http://163.25.95.214/ 現職 Associate Research Fellow 學歷 PhD, Department of Nuclear Science, National Tsing Hua University 經歷 2015/08 ~ present post 2012/01 ~ 2015/02 Deputy Director, Health Physics Division, Institute of Nuclear Energy Research 2000/06 ~ 2012/01 Associate Researcher, Physics Division, Institute of Nuclear Energy Research 1986/10 ~ 2000/06 Assistant Researcher, Physics Division, Institute of Nuclear Energy Research 研究領域 Radiation Imaging、 Proton PET、 Compton Camera、 PET/SPECT/CT Instrumentation、 Radiation Imaging Processing 近五年五篇代表著作 HY Tsai, HY Chen, MW Lee, Z Wang, SP Tseng, JH Hong, ML Jan*; “Experimental evaluation of depth-encoding absorber designs for prompt-gamma Compton imaging in proton therapy”, Radiation Measurements, 2019 127:106145. (*corresponding author) HM Huang and ML Jan; "Accuracy of using high-energy prompt gamma to verify proton beam range with a Compton camera: A Monte Carlo simulation study", Applied Radiation and Isotopes, 2018 142:173–180 ML Jan, MW Lee, HM Huang; “PSF reconstruction for Compton-based prompt gamma imaging” , Physics in Medicine and Biology, 2018 63(3): 035015 HM Huang, CC Liu, ML Jan and MW Lee; "A low-count reconstruction algorithm for Compton-based prompt gamma imaging", Physics in Medicine and Biology, 2018 63(8): 085013, ML Jan, IT Hsiao, HM Huang; “Use of a LYSO-based Compton camera for prompt gamma range verification in proton therapy”, Medical Physics 2017 44(12):6261-6269 獲獎 “An automatic exposure control system for a digital x-ray imaging device and method thereof”was awrded a Gold Medal in 2018 Taiwan Innotech Expo. “A scanning system for three-dimensional x-ray imaging” was awarded the Platinum Award in 2017 Taipei International Invention Show and Technomart Invention of “A projection method for three-dimensional radiation imaging” was awarded the Gold Medal in 2017 Taipei International Invention Show and Technomart “A reconstruction method for 3D tomography from 2D projection imaging” was awarded a Gold Medal in 2013 Taipei International Invention Show and Technomart “Design of a positron imager for breast imaging” was awarded the 10th National New Innovation Award in 2013 歷年計畫主持人研究計畫 2020/08 ~ 2022/07 Ministry of Science and Technology Grant Project—Development of an on-line positron imager for treatment response monitoring in charged-particle therapy 2020/03 ~ 2020/12 Industry-Academic Cooperation Program—Development of a 3D X-ray Imaging system 2019/08 ~ 2020/07 Ministry of Science and Technology Grant Project—Development of an on-line positron imaging monitor for chargedparticle therapy 2016/11 ~ 2021/04 Chang Gung Medical Research Project—Development of a Compton Imaging Detection System 2016/08 ~ 2019/07 Ministry of Science and Technology Grant Project—Development of a new prompt-gamma imaging camera for in-vivo proton range verification

趙自強 教授 電話、分機：(03)2118800 ext. 5385 Email：chaot@gap.cgu.edu.tw 實驗室網頁：https://scholar.google.com.tw/citations?user=2NRwW2EAAAAJ&hl=zh-TW 現職 2021/08 ~   長庚大學 醫學影像暨放射科學系 教授 學歷 PhD, Nuclear Engineering, Rensselaer Polytechnic Institute, USA MSc, Nuclear Sciences, National Tsing Hua University, Taiwan BS, Physics, National Tsing Hua University, Taiwan 經歷 2003/02 ~ 2011/07 長庚大學 醫學影像暨放射科學系 助理教授 2011/08 ~ 2021/07 長庚大學 醫學影像暨放射科學系 副教授 研究領域 蒙地卡羅、劑量學、輻射安全、放射物理 近五年五篇代表著作 Chiang, Y., Tan, C.M., Tung, C.J., Lee, C.C., and Chao, T.C., Lineal energy of proton in silicon by a microdosimetry simulation. Applied Sciences, 2021. 11(3): p. 1113. Lee, C.C., Wu, C.J., Huang, H.C., Wu, S.W., Cai, S.Y., Fan, K.H., Hong, J.H., Tung, C.J., Chu, C.H., and Chao, T.C., Dose impact of a brass aperture on low dose tails for a proton wobbling nozzle with a multileaf collimator—A Monte Carlo study. Radiation Physics and Chemistry, 2020. 167: p. 108367. Chiang, Y., Chao, T.C., Cho, I.C., Lee, C.C., Hong, J.H., Chu, C.H., and Tung, C.J., Silicon equivalent gas in silicon equivalent proportional counterMonte Carlo simulations. Radiation Physics and Chemistry, 2020. 167: p. 108259. Yu, P.C., Nien, H.H., Tung, C.J., Lee, H.Y., Lee, C.C., Wu, C.J., and Chao, T.C., CT-based MCNPX dose calculations for gynecology brachytherapy employing a Henschke applicator. Radiation Physics and Chemistry, 2017. 140: p. 392397. Chen, S.K., Chiang, B.H., Lee, C.C., Tung, C.J., Hong, J.H., and Chao, T.C., The impact of MCS models and EFAC values on the dose simulation for a proton pencil beam. Radiation Physics and Chemistry, 2017. 137: p. 2932. 歷年計畫主持人研究計畫 2021~2021 職業、民眾及環境輻射防護管制措施精進研析(110-2623-E-182-001-NU) 2020~ 2021 建立應用於加速器式硼捕獲中子治療之劑量評估系統(109-2314-B-182-020-) 2019~ 2020 微劑量學在質子治療和輻照的應用(108-2314-B-182 -012) 2017~ 2019 發展質子影像和質子斷層掃描作為射程驗證的工具(106-2314-B-182 -016 -MY2) 2016~ 2017 質子治療三維生物加權劑量的評估(II-III) (105-2314-B-182 -034)