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Chun-Chia Cheng, PhD

Chun-Chia Cheng PhD

TEL:(03)2118800 ext. 3864

Email:cccheng.biocompare@gmail.com

WEB:https://www.researchgate.net/profile/Chun-Chia-Cheng

現職

  • Assistant Research Fellow

學歷

  • Ph.D. Degree: Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taiwan.

經歷

  • 2015/12 ~ 2016/07 Postdoctoral Fellow in Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
  • 2016/09 ~ 2018/09 Assistant Researcher in Hematology and Oncology, Mackay Memorial Hospital, Taipei, Taiwan.
  • 2018/10 ~ 2019/07 Postdoctoral Fellow in Institute of Molecular and Genomic Medicine, National Health Research Institute, Taiwan.

研究領域

Radiobiology, Cancer Biology, Cancer Immunology, Biotechnology

近五年五篇代表著作

  • Chun-Chia Cheng, Yi-Fang Chang, Ai-Sheng Ho, Zong-Lin Sie, Jungshan Chang, Cheng-Liang Peng, and Chun-Chao Chang. Irradiation mediates IFNα and CXCL9 expression in non-small cell lung cancer to stimulate CD8+ T cells activity and migration toward tumors. Biomedicines. 2021, 9, 1349. (SCI/IF: 6.08)
  • Chun-I Wang, Yi-Fang Chang, Zong-Lin Sie, Ai-Sheng Ho, Jungshan Chang, Cheng-Liang Peng and Chun-Chia Cheng*. Irradiation Suppresses IFNγ-Mediated PD-L1 and MCL1 Expression in EGFR-Positive Lung Cancer to Augment CD8+ T Cells Cytotoxicity. Cells. 2021, 10(10), 2515. *Corresponding author. (SCI/IF: 6.6)
  • Chun-Chia Cheng, Hsin-Chi Lin, Ya-Wen Chiang, Jungshan Chang, Zong-Lin Sie, Bi-Ling Yang, Ken-Hong Lim, MD, Cheng-Liang Peng, Ai-Sheng Ho, Yi-Fang Chang. Nicotine exhausts CD8+ T cells against tumor cells through increasing miR-629-5p to repress IL2RB-mediated granzyme B expression. Cancer Immunology, Immunotherapy. 2020, 70(5):1351-1364. (SCI/IF: 6.968)
  • Chun-Chia Cheng, Bi-Ling Yang, Wen-Chao Chen, Ai-Sheng Ho, Zong-Lin Sie, Hsin-Chi Lin and Chun-Chao Chang. STAT3 Mediated miR-30a-5p Inhibition Enhances Proliferation and Inhibits Apoptosis in Colorectal Cancer Cells. International Journal of Molecular Sciences. 2020, 21:7315. (SCI/IF: 5.923)
  • Chun-Chia Cheng, Wan-Yu Yang, Ming-Chen Hsiao, Kuan-Hao Lin, Hao-Wei Lee, and Chiou-Hwa Yuh. Transcriptomically Revealed Oligo-Fucoidan Enhances the Immune System and Protects Hepatocytes via the ASGPR/STAT3/HNF4A Axis. Biomolecules. 2020, 10:898. (SCI/IF: 4.879)

歷年計畫主持人研究計畫

  • 2021 ~ 2022 Grant from the Ministry of Science and Technology of Taiwan. (MOST 110-2314-B-182-031), Study for investigating the mechanism of cancer cells on exhausting immunological cells and detected by a nuclear imaging platform (2/2)
  • 2020 ~ 2021 Grant from the Ministry of Science and Technology of Taiwan. (MOST 109-2314-B-182-011), Study for investigating the mechanism of cancer cells on exhausting immunological cells and detected by a nuclear imaging platform (1/2)