about

Center description

The Center for Molecular and Clinical Immunology (CMCI) is a research center affiliated with the School of Medicine of Chang Gung University. At present, the center is staffed by a director, several principal investigators, four research assistants, and one technician.  

CMCI is located on the 6th floor of the First Medical Building.   

lab researcher

Our goal

The goal of CMCI is to study the molecular and physiological immune mechanisms underlying human health and disease. Equipped with an abundance of clinical resources from the Chang Gung system, the center focuses on clinical issues involving special diseases and clinical needs of the local area. The center actively seeks opportunities for drug development and the industry-university cooperation, and we ultimately hope that our research results can translate to the clinic and help relieve human suffering.  
 At present, the main research direction of the center is the host mechanism of human infection immunity, especially immunogenetic loss and anti-cytokine autoantibodies.  
We envision that the center will expand into two new research directions:

- Immune cell therapy 
- Cancer and metabolic immunity 

lab equipment

Research direction and specialties

Disease-centered research
The center hugely benefits from the Chang Gung system's clinical resources, and provides an environment for close collaboration between immunologists and joint clinical personnel. Therefore, human diseases are always kept at the forefront of our research, and it is hoped that the center's output can be fed back to clinics as soon as possible.


A cutting-edge human immunity research platform
Human immunology is the center's main field of interest, so we focus on the development of core technologies and platforms related to translational medical research. At present, the center has established a human single B cell colonization platform (including selection, professional protein production platform, antibody physiological function and affinity analysis instruments and platforms), has successfully completed antibody selection, and has helped to develop several drugs and contribute to technology improvements. At present, we are actively developing new research platforms, such as an immunoassay platform with high-throughput flow cytometry as the core, cell immunotherapy research platform, etc.

The center also conducts multidisciplinary research in the fields of physiology, microbiology, mycology, nanomaterials, and bioengineering, and actively collaborates with universities, research institutes, and biomedical companies in China and abroad. These include:
  • The impact of inflammation on health and disease.
  • Host-pathogen interactions and pathogenic mechanisms.
  • The role of the gut microbiota in obesity and type 2 diabetes.
  • Effect of mineral organic nanoparticles on physiological processes.
  • Bacterial clustering and biofilm formation.
  • Immunological properties of medicinal mushrooms.
  • Use natural health supplements to prevent disease.
Research conducted by CMCI is based on the most advanced technologies and expert knowledge in the fields of genomics, proteomics and metabolomics. We are committed to combining the multiple disciplines of research to bridge the gap between traditional medical practice and current scientific knowledge, with the expectation of significant advances in biomedical sciences and the introduction of the latest research results into clinical applications.


International Academic Cooperation and Exchange
In order to bring first-class research to Taiwan, CMCI actively cooperates with internationally renowned research units and laboratories. We are actively working with Professor Casanova from the Rockefeller University (United States). Professor Casanova has cooperated with dozens of domestic and foreign laboratories, including the Institut Pasteur (France), the Imagine Institute (France), the University of Lausanne (Switzerland), and the University of Hiroshima (Japan). He is also a major partner of our Formosa Immunology Spring School and Symposium (FISS).
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