research

2023

Selected works

  1. Anti-IL-17A antibody-associated de novo vitiligo: Case report and review of literature. Su HJ, Chan YP, Shen PC, Ku CL, Ng CY. Front Immunol. 2023 Jan 18;13:1077681. doi: 10.3389/fimmu.2022.1077681. [PubMed]
  2. Functional characterization of the MyD88 homologs in Strongylocentrotus purpuratus. Chou ST, Lin TM, Yang HY, Fugmann SD. Dev Comp Immunol. 2023 Feb;139:104580. doi: 10.1016/j.dci.2022.104580. [PubMed]
  3. Metabolic challenges and interventions in CAR T cell therapy. Peng JJ, Wang L, Li Z, Ku CL, Ho PC. Sci Immunol. 2023 Apr 14;8(82):eabq3016. doi: 10.1126/sciimmunol.abq3016. [PubMed]
  4. Targeting the elevated IFN-γ in vitiligo patients by human anti- IFN-γ monoclonal antibody hampers direct cytotoxicity in melanocyte. Ng CY, Chan YP, Chiu YC, Shih HP, Lin YN, Chung PH, Huang JY, Chen HK, Chung WH, Ku CL. J Dermatol Sci. 2023 Jun;110(3):78-88. doi: 10.1016/j.jdermsci.2023.04.006. [PubMed]  
  5. Reductive carboxylation epigenetically instructs T cell differentiation. Jaccard A, Wyss T, Maldonado-Pérez N, Rath JA, Bevilacqua A, Peng JJ, Lepez A, Von Gunten C, Franco F, Kao KC, Camviel N, Martín F, Ghesquière B, Migliorini D, Arber C, Romero P, Ho PC, Wenes M. Nature. 2023 Sep;621(7980):849-856. doi: 10.1038/s41586-023-06546-y. [PubMed] 
  6. Regulatory circuits of mitophagy restrict distinct modes of cell death during memory CD8+ T cell formation. Franco F, Bevilacqua A, Wu RM, Kao KC, Lin CP, Rousseau L, Peng FT, Chuang YM, Peng JJ, Park J, Xu Y, Cassotta A, Yu YR, Speiser DE, Sallusto F, Ho PC. Sci Immunol. 2023 Sep 29;8(87):eadf7579. doi: 10.1126/sciimmunol.adf7579. [PubMed]
  7. Leptospirosis: A Potential Culprit for Chronic Kidney Disease of Uncertain Etiology. Premarathne SS, Gamage C, Chandrajith R, Ratnatunge NV, Wijetunge S, Wazil A, Chou LF, Ko YC, Huang CT, Yang HY, Fonseka A, Sonnadara T, Herath D, Hewavitharane P, Yang CW, Nanayakkara N. Nephron. 2023;147(8):510-520. doi: 10.1159/000528703. Epub 2023 Feb 21.[PubMed]
  8. Transcriptome landscape reveals the chronic inflammatory response in kidneys affected by the combinatory effect of leptospirosis and nephrotoxic injury. Chou LF, Huang CW, Yang HY, Tian YC, Chang MY, Hung CC, Chen KH, Hsu SH, Tsai CY, Ko YC, Chen TW, Yang CW. Genomics. 2023 May;115(3):110624. doi: 10.1016/j.ygeno.2023.110624 [PubMed]

2022

  1. Thrombin-Activated Platelets Protect Vascular Endothelium against Tumor Cell Extravasation by Targeting Endothelial VCAM-1. Lee CM, Chang ML, Chen RH, Chen FW, Liu JC, Kuo SL, Peng HH. Int J Mol Sci. 2022 Mar 22;23(7):3433. doi: 10.3390/ijms23073433 [PubMed]
  2. Skin Interstitial Fluid and Plasma Multiplex Cytokine Analysis Reveals IFN-γ Signatures and Granzyme B as Useful Biomarker for Activity, Severity and Prognosis Assessment in Vitiligo. Ng CY, Chiu YC, Chan YP, Lin YJ, Chung PH, Chung WH, Ku CL.Front Immunol. 2022 Apr 7;13:872458. doi: 10.3389/fimmu.2022.872458. [PubMed]
  3. Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response. Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. J Exp Med. 2022 Sep 5;219(9):e20212126. doi: 10.1084/jem.20212126. [PubMed]
  4. Cryptococcus gattii infection as the major clinical manifestation in patients withautoantibodies against Granulocyte-Macrophage Colony-Stimulating Factor. Wang SY, Lo YF, Shih HP, Ho MW, Yeh CF, Peng JJ, Ting HT, Lin KH, Huang WC, Chen YC, Chiu YH, Hsu CW, Tseng YT, Wang LS, Lei WY, Lin CY, Aoh Y, Chou CH, Wu TY, Ding JY, Lo CC, Lin YN, Tu KH, Lei WT, Kuo CY, Chi CY, Ku CL.J Clin Immunol. 2022 Nov;42(8):1730-1741. doi: 10.1007/s10875-022-01341-2. [PubMed] 
  5. Autoantibodies against type I IFNs in patients with critical influenza pneumonia. Zhang Q, Pizzorno A, Miorin L, Bastard P, Gervais A, Le Voyer T, Bizien L, Manry J, Rosain J, Philippot Q, Goavec K, Padey B, Cupic A, Laurent E, Saker K, Vanker M, Särekannu K; COVID Human Genetic Effort; Etablissement Français du Sang Study Group; Constances Cohort; 3C-Dijon Study; Cerba HealthCare Group; Lyon Antigrippe Working Group; REIPI INF Working Group; García-Salum T, Ferres M, Le Corre N, Sánchez-Céspedes J, Balsera-Manzanero M, Carratala J, Retamar-Gentil P, Abelenda-Alonso G, Valiente A, Tiberghien P, Zins M, Debette S, Meyts I, Haerynck F, Castagnoli R, Notarangelo LD, Gonzalez-Granado LI, Dominguez-Pinilla N, Andreakos E, Triantafyllia V, Rodríguez-Gallego C, Solé-Violán J, Ruiz-Hernandez JJ, Rodríguez de Castro F, Ferreres J, Briones M, Wauters J, Vanderbeke L, Feys S, Kuo CY, Lei WT, Ku CL, Tal G, Etzioni A, Hanna S, Fournet T, Casalegno JS, Queromes G, Argaud L, Javouhey E, Rosa-Calatrava M, Cordero E, Aydillo T, Medina RA, Kisand K, Puel A, Jouanguy E, Abel L, Cobat A, Trouillet-Assant S, García-Sastre A, Casanova JL.J Exp Med. 2022 Nov 7;219(11):e20220514. doi: 10.1084/jem.20220514. [PubMed]
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