長庚大學

經歷

國立清華大學學士後醫學系約聘專任副教授

林口長庚紀念醫院解剖病理科主治醫師

和信醫院病理科住院醫師

林口長庚紀念醫院解剖病理科住院醫師

研究計畫(近三年)

大腸直腸癌三級淋巴結構的空間和功能特徵：對預後和新興治療的影響 (2024/08/01 至2025/07/31 國科會)

論文發表(近五年)

1. Anna See,Min‐Cun Yang,Yenlin Huang,Tsung‐You Tsai,Chi‐Yin Lee,Pin‐Hsuan Huang,Ti‐Yung Tseng,Shu‐Hang Ng,Kai‐Ping Chang (2024, Dec). Radiological Sublingual Space Invasion in Tongue Squamous Cell Carcinoma: Clinicopathological Associations and Impact on Survival. Otolaryngology–Head and Neck Surgery.

2. Tsung-You Tsai,Wing-Keen Yap,Ting-Hao Wang,Yi-An Lu,Anna See,Yu-Feng Hu,Yenlin Huang,Huang-Kai Kao,Kai-Ping Chang (2024, Oct). Upfront Surgery Versus Upfront Concurrent Chemoradiotherapy as Primary Modality in Hypopharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis. Journal of Otolaryngology - Head & Neck Surgery, 53, 19160216241293633.

3. Tsz Yin Voravitvet,Yenlin Huang,Sawarin Voravitvet,Juan Larsson,Po-Hao Lien,David Chwei-Chin Chuang,Johnny Chuieng-Yi Lu,Tommy Nai-Jen Chang (2024, Jul). Dynamic Eye Closure Restoration in Facial Palsy with Neurotized Platysma Muscle Graft in Rats. Journal of Reconstructive Microsurgery.

4. I-Hsin Huang,Yen-Lin Huang,Kuan-Yu Chen (2024, May). Granulomatous mycosis fungoides on the wrist of a middle-aged man. Dermatologica Sinica, 42(2), 172-173.

5. Tsung‐You Tsai,Pin‐Chun Chiang,Wing‐Keen Yap,Yenlin Huang,Anna See,Shao‐Yu Hung,Chuieng‐Yi Lu,Chien‐Yu Lin,Tung‐Chieh Joseph Chang,Huang‐Kai Kao,Kai‐Ping Chang (2024, May). Postoperative radiotherapy versus surgery alone in pN1 oral cavity cancer patients: A meta‐analysis. Laryngoscope Investigative Otolaryngology, 9(3), e1260.

6. Hsin-Pai Li,Chen-Yang Huang,Kar-Wai Lui,Yin-Kai Chao,Chun-Nan Yeh,Li-Yu Lee,Yenlin Huang,Tung-Liang Lin,Yung-Chia Kuo,Mei-Yuan Huang,Hsien-Chi Fan,An-Chi Lin,Chia-Hsun Hsieh,Kai-Ping Chang,Chien-Yu Lin,Hung-Ming Wang,Mei Chao,Jai-Shin Liu,Yu-Sun Chang,Cheng-Lung Hsu (2023, Dec). Nasopharyngeal carcinoma patient-derived xenograft mouse models reveal potential drugs targeting cell cycle, mTOR, and autophagy pathways. Translational Oncology, 38, 101785.

7. Tzu-Chi Lo,Jing-Yan Cheng,Chien-Wei Lee,Jung-Tung Hung,Chun-Cheng Lin,Hsiao-Fong Yeh,Bei-Chia Yang,Yenlin Huang,Hsien-Ming Wu,Alice L. Yu,John Yu (2023, Nov). Priming of macrophage by glycosphingolipids from extracellular vesicles facilitates immune tolerance for embryo-maternal crosstalk. Developmental Cell, 58(22), 2447-2459.

8. Chien-Chia Huang,Po-Hung Chang,Yen-Lin Huang,Ta-Jen Lee,Chi-Che Huang,Pei-Wen Wu (2023, Oct). Clinical Characteristics of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps in Adolescents. Journal of Asthma and Allergy, 16, 1197-1206.

9. Tsai-Hsien Hung,Chun-Nan Yeh,Jung-Tung Hung,Chiao-En Wu,Chien-Wei Lee,John Yu,Alice L Yu,Yenlin Huang (2023, Oct). Globo H ceramide is an independent prognostic marker for gallbladder cancer.. American journal of cancer research, 13(10), 4811–4821.【為通訊作者】

10. Yi‐Chan Lee,Li‐Yu Lee,Yenlin Huang,Huang‐Kai Kao,Ya‐Ting Chang,Shao‐Yu Hung,Chuieng‐Yi Lu,Yu‐Sun Chang,Jau‐Song Yu,Kai‐Ping Chang (2023, Oct). Comparison between a novel salivary marker and several clinical prognosticators in oral cavity cancer. Laryngoscope Investigative Otolaryngology, 8(6), 1547-1556. 【為第一作者】

11. Yu-Hsi Fan,Kai-Yi Shih,Pei-Wen Wu,Yen-Lin Huang,Ta-Jen Lee,Chi-Che Huang,Po-Hung Chang,Chien-Chia Huang (2023, Oct). Predicting the Probability of the Incidence of Maxillary Sinus Fungus Ball in Patients Using Nomogram Models. Diagnostics, 3(19), 3156.

12. Chiao-En Wu,Yi-Hua Liao,Cheng-Lin Wu,Ruoh-Fang Yen,Chia-Chi Lin,Muh-Hwa Yang,Chueh-Chuan Yen,Wu-Chou Su,Chia-Jui Yen,Yi-Fang Chang,Ming-Fang Wu,Youngsen Yang,Chen-Yuan Lin,Wen-Chi Yang,Hui-Ching Wang,Cheng-Yuan Li,Yin-Yu Ho,Yao-Yu Chang,Chieh-Shan Wu,Hsiu-Cheng Hsu,Kuang-Hua Chen,Yenlin Huang,Chih-Jung Chen,Pei-Ju Chuang,Yung-Chi Lai,Yu-Yi Huang,Neng-Chuan Tseng,Yi-Ting Huang,Chia-Yu Chu,John Wen-Cheng Chang (2023, Sep). Clinical practice consensus for the diagnosis and management of melanoma in Taiwan. Journal of the Formosan Medical Association.

13. Yu-Han Hsueh,Yenlin Huang,Chun-Bing Chen (2023, Sep). Angioimmunoblastic T-cell lymphoma presenting as extensive pseudovesicular papuloplaques. Dermatologica Sinica, 10.4103/ds.DS-D-23-00040.

14. John Wen‐Cheng Chang,Chien‐Jung Huang,Wen‐Kuan Huang,Yu‐Chao Wang,Jia‐Juan Hsieh,Yao‐Yu Chang,Yen‐Lin Huang,Chia‐Ling Wu,Yeh‐Han Wang,Shu‐Jen Chen,Kien Thiam Tan,Chiao‐Ping Chen,Chiao‐En Wu (2023, Aug). Genomic and tumour microenvironmental biomarkers of immune checkpoint inhibitor response in advanced Taiwanese melanoma. Clinical & Translational Immunology.

15. Tsai-Hsien Hung,Yenlin Huang,Chau-Ting Yeh,Chun-Nan Yeh,John Yu,Chun-Cheng Lin,Shih-Pin Chiou,Pei-Yun Chiang,Jung-Tung Hung,Alice L. Yu (2023, Jun). High expression of embryonic stem cell marker SSEA3 confers poor prognosis and promotes epithelial mesenchymal transition in hepatocellular carcinoma. Biomedical Journal.

16. Wei-Chen Yen,Kai-Ping Chang,Cheng-Yi Chen,Yenlin Huang,Ting-Wen Chen,Hsing-Wen Cheng,Jui-Shan Yi,Chun-Chia Cheng,Chih-Ching Wu,Chun-I Wang (2023, Jun). MFI2 upregulation promotes malignant progression through EGF/FAK signaling in oral cavity squamous cell carcinoma. Cancer Cell International, 23(1), 112.

17. Tzong-Yun Tsai,Chun-Kai Liao,Bang-Yan Zhang,Yen-Lin Huang,Wen-Sy Tsai,Jeng-Fu You,Chien-Yuh Yeh,Pao-Shiu Hsieh (2023, May). Perianal Basal Cell Carcinoma—A Systematic Review and Meta-Analysis of Real-World Data. Diagnostics, 13(9), 1650.

18. Yi-Teng Hung,Yen-Wen Chen,Yen-Lin Huang,Yu-Jr Lin,Chun-Bing Chen,Wen-Hung Chung (2023, Apr). Acute graft-versus-host disease presenting as Stevens-Johnson syndrome and toxic epidermal necrolysis: A retrospective cohort study. Journal of the American Academy of Dermatology, 88(4), 792-801.

19. Yu-Tzu Chan,Ruey-Jen Lin,Ya-Hui Wang,Tsai-Hsien Hung,Yenlin Huang,John Yu,Jyh-Cherng Yu,Alice L. Yu (2023, Apr). The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells. Cell Communication and Signaling, 21(1), 81.

20. Chia-Chun Chen,Pi-Yueh Chang,Yu-Sun Chang,Jeng-Fu You,Err-Cheng Chan,Jinn-Shiun Chen,Wen-Sy Tsai,Yen-Lin Huang,Chung-Wei Fan,Hung-Chih Hsu,Jy-Ming Chiang (2023, Feb). MicroRNA-based signature for diagnosis and prognosis of colorectal cancer using residuum of fecal immunochemical test. Biomedical Journal, 46(1), 144-153.

21. Chia-Chi Yeh,Huang-Kai Kao,Yenlin Huang,Tsung-You Tsai,Chi-Kuang Young,Shao-Yu Hung,Chuieng-Yi Lu,Kai-Ping Chang (2023, Jan). Discovering the Clinical and Prognostic Role of Pan-Immune-Inflammation Values on Oral Cavity Squamous Cell Carcinoma. Cancers, 15(1), 322.

22. Tsung-You Tsai,Huang-Kai Kao,Yenlin Huang,Ya-Ting Chang,Chi-Kuang Young,Shao-Yu Hung,Yu-Sun Chang,Jau-Song Yu,Kai-Ping Chang (2022, Dec). Plasma Matrix Metalloproteinase-1 as a Prognostic Biomarker in Oral Cavity Squamous Cell Carcinoma. Cancer Management and Research, 14, 3459-3468.

23. Yi‐Teng Hung,Wen‐Hung Chung,Yen‐Lin Huang,Chun‐Bing Chen (2022, Jun). Immune checkpoint inhibitor–associated panniculitis: Clinicopathological features and cytokine profiles. Journal of the European Academy of Dermatology and Venereology.

24. Huan-Chieh Cho, Yenlin Huang, Jung-Tung Hung, Tsai-Hsien Hung, Kai-Chun Cheng, Yun-Hen Liu, Ming-Wei Kuo, Sheng-Hung Wang, Alice L. Yu, John Yu (2022, Feb). Puf-A promotes cancer progression by interacting with nucleophosmin in nucleolus. Oncogene, 41(8):1155-1165. 【為第一作者】

25. Yi‐Teng Hung,Yen‐Lin Huang,Yao‐Yu Chang,Wei‐Ti Chen (2022, Feb). Unilateral linear purpuric rash heralding SARS‐CoV‐2 vaccine‐induced immune thrombotic thrombocytopenia. Journal of the European Academy of Dermatology and Venereology.

26. Tsai-Hsien Hung, Jung-Tung Hung, Chiao-En Wu, Yenlin Huang, Chien-Wei Lee, Chau-Ting Yeh, Yi-Hsiu Chung, Fei-Yun Lo, Li-Chun Lai, John K. Tung, John Yu, Chun-Nan Yeh, Alice L. Yu (2022, Jan). Globo H is a promising theranostic marker for intrahepatic cholangiocarcinoma. Hepatology Communications, 6(1):194-208.

27. Tsai TY, Andrea Iandelli, Filippo Marchi, Huang YL, Tai SF, Hung SY, Kao HK, Chang KP (2022, Jan). The Prognostic Value of Lymph Node Burden in Oral Cavity Cancer: Systematic Review and Meta-Analysis. Laryngoscope, 132(1):88-95.

28. Wu PW, Lee TJ, Yang SW, Huang YL, Lee YS, Ho CF, Huang CC (2021, Dec). Differences in clinical and imaging presentation of maxillary sinus fungus ball with and without intralesional hyperdensity. Scientific Reports, 11(1):23945.

29. Chen TW, Chang KP, Cheng CC, Chen CY, Hong SW, Sie ZL, Cheng HW, Yen WC, Huang YL, Liu SC, Wang CI (2021, Nov). Characterization of Recurrent Relevant Genes Reveals a Novel Role of RPL36A in Radioresistant Oral Squamous Cell Carcinoma. Cancers (Basel), 13(22):5623.

30. Stephen Yuan HC, Chang SC, Huang YL, Liu HP (2021, Oct). Serum Level of Tumor-Overexpressed AGR2 Is Significantly Associated with Unfavorable Prognosis of Canine Malignant Mammary Tumors. Animals (Basel), 11(10):2923.

31. Lu LY, Yen H, Sun PL, Huang YL, Lu CW (2021, Sep). Juvenile folliculotropic mycosis fungoides mimicking tinea capitis: A case report and literature review. Dermatologica Sinica , 39(3):145-146 .

32. Tsung-You Tsai, Yenlin Huang, Andrea Iandelli, Shiao-Fwu Tai, Shao-Yu Hung, Huang-Kai Kao, Kai-Ping Chang (2021, Sep). The role of postoperative radiotherapy in pN1 oral cavity cancer without extranodal extension. World Journal of Surgical Oncology, 19(1):279.

33. Pushpanjali Gupta, Yenlin Huang, Prasan Kumar Sahoo, Jeng-Fu You, Sum-Fu Chiang, Djeane Debora Onthoni, Yih-Jong Chern, Kuo-Yu Chao, Jy-Ming Chiang, Chien-Yuh Yeh, Wen-Sy Tsai (2021, Aug). Colon Tissues Classification and Localization in Whole Slide Images Using Deep Learning. Diagnostics, 11(8):1398. 【為第一作者】

34. Li HP, Huang CY, Lui KW, Chao YK, Yeh CN, Lee LY, Huang YL, Lin TL, Kuo YC, Huang MY, Lai YR, Yeh YM, Fan HC, Lin AC, Jason Hsieh CH, Chang KP, Lin CY, Wang HM, Chang YS, Hsu CL (2021, Jun). Combination of Epithelial Growth Factor Receptor Blockers and CDK4/6 Inhibitor for Nasopharyngeal Carcinoma Treatment. Cancers (Basel), 13(12): 2954.

35. Chuang HH, Hsu JF, Chuang LP, Chiu CH, Huang YL, Li HY, Chen NH, Huang YS, Chuang CW, Huang CG, Lai HC, Lee LA (2021, May). Different Associations between Tonsil Microbiome, Chronic Tonsillitis, and Intermittent Hypoxemia among Obstructive Sleep Apnea Children of Different Weight Status: A Pilot Case-Control Study.. Journal of Personalized Medicine, 11(6):486.

36. Wang YH, Chan YT, Hung TH, Hung JT, Kuo MW, Wang SH, Huang YL, Lin YJ, Chen SC, Yu JC, Wu JC, Yu J, Yu AL (2021, Apr). Transmembrane and coiled-coil domain family 3 (TMCC3) regulates breast cancer stem cell and AKT activation. Oncogene, 40(16):2858-2871 .

37. Liao YM, Wang YH, Hung JT, Lin YJ, Huang YL, Liao GS, Hsu YL, Wu JC, Yu AL (2021, Jan). High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer.. Breast Cancer Research, 23(1):5.

38. Yenlin Huang, Chieh Lin, Huang-Kai Kao, Shao-Yu Hung, Hung-Ju Ko, Yu-Chen Huang, Yu-Liang Chang, Kai-Ping Chang (2020, Sep). Digital Image Analysis of CD8+ and CD3+ Tumor-Infiltrating Lymphocytes in Tongue Squamous Cell Carcinoma.. Cancer Management and Research, 12: 8275-8285. (SCI, 145/244, Oncology). 【為第一作者】

39. Sakarya AH, Do NTK, Huang YL, Lu JC, Chang TN, Chuang DC (2020, Jul). Effect of Degree of Arterial Inflow on a Functioning Free Muscle Transplantation in a Rat Gracilis Model. Journal of Reconstructive Microsurgery, 36(6):458-465.

40. Chu YD, Lin WR, Lin YH, Kuo WH, Tseng CJ, Lim SN, Huang YL, Huang CH, Wu TJ, Lin KH, Yeh CT (2020, Jun). COX5B-Mediated Bioenergetic Alteration Regulates Tumor Growth and Migration by Modulating AMPK-UHMK1-ERK Cascade in Hepatoma.. Cancers (Basel), 12(6), 1646. (SCI, 37/244, Oncology).

41. Yang CY, Liu CR, Chang YF, OuYang CN , Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL , Tsai TL, Liu H, Tseng CP, Chang YC, Wu CC, Chang KP (2020, Jun). Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts.. Cancers (Basel), 12(7), 1726. (SCI, 37/244, Oncology).

42. Tay ZY, Kao HJ, Lien KH, Hung SH, Huang Y, Tsang NM, Chang KP (2020, May). The impact of preoperative glycated hemoglobin levels on outcomes in oral squamous cell carcinoma. Oral Diseases, 26(7), 1449–1458. (SCI, 19/91, dentistry, oral surgery & medcine).

43. Wu PW, Huang CC, Yang SW, Huang Y, Huang CC, Chang PH, Lee YS, Lee TJ (2020, Apr). Endoscopic sinus surgery for pediatric patients: Prognostic factors related to revision surgery. Laryngoscope, 130(4), 1051-1055. (SCI, 10/42, otolaryngology).

44. Renda L, Tsai TY, Huang JJ, Ito R, Hsieh WC, Kao HK, Hung SY, Huang Y, Huang YC, Chang YL, Cheng MH, Chang KP (2020, Jan). A nomogram to predict osteoradionecrosis in oral cancer after marginal mandibulectomy and radiotherapy. Laryngoscope, 130(1), 101-107. (SCI, 12/42, otolaryngology).

45. Gupta P, Chiang SF, Sahoo PK, Mohapatra SK, You JF, Onthoni DD, Hung HY, Chiang JM, Huang Y, Tsai WS (2019, Dec). Prediction of Colon Cancer Stages and Survival Period with Machine Learning Approach. Cancers (Basel), 11(12), pii: E2007. (SCI, 31/230, oncology).

46. Wang CI, Kao HK, Chen TW, Huang Y, Cheng HW, Yi JS, Hung SY, Wu CS, Lee YS, Chang KP (2019, Dec). Characterization of Copy Number Variations in Oral Cavity Squamous Cell Carcinoma Reveals a Novel Role for MLLT3 in Cell Invasiveness. Oncologist, 24(12), e1388-e1400. (SCI, 46/230, oncology).

47. Chang JW, Huang YL, Chang YY, Lo YF, Ho TY, Huang YT, Chen HW, Wu CE (2019, Nov). Sentinel Lymph Node Biopsy Was Associated With Favorable Survival Outcomes For Patients With Clinically Node-Negative Asian Melanoma. Cancer Manag Res, 11, 9655-9664. (SCI, 168/230, oncology).

48. Chang JW, Chang YY, Huang YL, Lo YF, Ho TY, Huang YT, Chen HW, Yeh CN, Wu CE (2019, Oct). Merkel cell carcinoma in Taiwan: A series of 24 cases and literature review. Medicine (Baltimore), 98(42), e17538. (SCI, 69/160, medicine, general & internal).

49. Hsu CW, Chang KP, Huang Y, Liu HP, Hsueh PC, Gu PW, Yen WC, Wu CC (2019, Oct). Proteomic Profiling of Paired Interstitial Fluids Reveals Dysregulated Pathways and Salivary NID1 as a Biomarker of Oral Cavity Squamous Cell Carcinoma. Mol Cell Proteomics, 18(10), 1939-1949. (SCI, 7/79, biochemical research methods).

50. Wu CC, Chang SC, Zeng GY, Chu HW, Huang Y, Liu HP (2019, Jul). Proteome Analyses Reveal Positive Association of COL2A1, MPO, TYMS, and IGFBP5 with Canine Mammary Gland Malignancy. Proteomics Clin Appl, 13(4), e1800151.

51. Wu PW, Huang CC, Yang SW, Huang Y, Huang CC, Chang PH, Lee YS, Lee TJ (2019, Jun). Endoscopic sinus surgery for pediatric patients: Prognostic factors related to revision surgery. Laryngoscope, (4):1051-1055. (SCI, 12/42, otolaryngology).

52. Dante de Paz, Kai-Ping Chang, Huang-Kai Kao, William Wei-Kai Lo, Yu-Chen Huang, Yu-Liang Chang, Yenlin Huang (2019, May). Clinical Implications of Tumor-Associated Tissue Eosinophilia in Tongue Squamous Cell Carcinoma. Laryngoscope, 129(5), 1123-1129. (SCI, 12/42, otolaryngology). 【為通訊作者】

53. Ho CF, Lee TJ, Wu PW, Huang CC, Chang PH, Huang YL, Lee YL, Huang CC (2019, May). Diagnosis of a maxillary sinus fungus ball without intralesional hyperdensity on computed tomography. Laryngoscope, 129(5), 1041-1045. (SCI, 12/42, otolaryngology).

54. Tsai CN, Tsai CL, Yi JS, Kao HK, Huang Y, Wang CI, Lee YS, Chang KP (2019, Mar). Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep, 9(1), 5197. (SCI, 15/69, multidisciplinary sciences).

55. Chang TN, Chen KT, Gorden T, Daniel BW, Hernon C, Shafarenko M, Huang YL, Lu JC, Chuang DC (2019, Jan). Vascularized Brachial Plexus Allotransplantation-An Experimental Study in Brown Norway and Lewis Rats. Transplantation, 103(1), 149-159. (SCI, 10/203, surgery).

長庚大學

黃彥霖

學歷

經歷

學會與認證

研究計畫(近三年)

論文發表(近五年)