長庚大學

學歷

經歷

2015/08~  長庚大學專任教授

2012~2022 高雄長庚醫院人體生物資料庫主任

2007~2015 長庚大學專任副教授

2003~2007 長庚大學助理教授

2002~2010 高雄長庚醫院解剖病理科主任

1998~1999 長庚護專講師

1998~2002 輔英技術學院講師

1997~1998 美國約翰霍普金斯大學研究員

1994~     高雄長庚醫院病理科主治醫師

1993~1994 高雄長庚醫院病理科住院總醫師

1990~1993 高雄長庚醫院病理科住院醫師

學會與認證

台灣病理學會

台灣個人化醫學研究學會

台灣頭頸部腫瘤醫學會

United states and Canadian Academy of Pathology

Asia-Australasia Pulmonary Pathology Society (President-elect)

研究計畫(近三年)

1. DLK1訊息調節惡性卵巢癌細胞之癌幹細胞化，化療抗藥性與免疫監控之研究，國科會計畫(2022/08/01~2023/07/31)

2. 在Sorafenib抗藥性肝癌中探討cyclooxygenase-2 / prostaglandin E2訊息傳遞於癌症幹細胞與免疫監控上扮演的角色，長庚醫學研究計畫(2022/11/01~2025/10/31)

3. 研究Delta‑like 1 Homolog (DLK1)在肝癌T細胞免疫監控與腫瘤進程的角色，國科會計畫(2023/08/01~2026/07/31)

近年論文發表

1.     Huang CC*, Kuo HM*, Wu PC, Cheng SH, Chang TT, Chang YC, Kung ML, Wu DC, Chuang JH, Tai MH. Soluble delta-like 1 homolog (DLK1) stimulates angiogenesis through Notch 1/Akt/eNOS signaling in endothelial cells. Angiogenesis 2018 May;21(2):299-312.  (SCI) (*Co-first author)

2.     Huang CC*, Cheng SH, Wu CH, Li WY, Wang JS, Kung ML, Chu TH, Huang ST, Feng CT, Huang SC, Tai MH*. Delta-like 1 homologue promotes tumorigenesis and epithelial-mesenchymal transition of ovarian high-grade serous carcinoma through activation of Notch signaling. Oncogene 2019 April;38:3201-3215.  (SCI) (First author and *co-corresponding author)

3.     Chen CM, Chu TH, Chou CC, Chien CY, Wang JS, Huang CC*. Exosome-derived microRNAs in oral squamous cell carcinomas impact disease prognosis. Oral Oncol 2021 Sep;120:105402. (SCI) (Corresponding author)

4.     Chu TH, Chou YW, Lin SL, Lin SF, Chen HH, Hu WH, Chen YY, Chang-Chien GP, Chang JH, Tsai MC, Huang CC*. A pilot study examining the relationship between environmental contaminants and colorectal cancer at a single medical institute in Taiwan. Taiwan J Public Health 2021 Oct;40(4):382-393. (Corresponding author)

5.     Wang CC, Huang KT, Chang HC, Tseng CC, Lai CH, Lan J, Liu TT, Huang CC*, Lin MC*. Comprehensive analysis of PD-L1 in non-small cell lung cancer with emphasis on survival benefit, impact of driver mutation and histological types, and archival tissue. Thorac Cancer 2022 Jan;13:38-47. (SCI) (Co-corresponding author)

6.     Kuo TY, Huang CC, Shieh SJ, Wang YB, Lin MJ, Wu MC, Huang LLH. Skin wound healing assessment via an optimized wound array model in miniature pigs. Sci Rep 2022 Jan;12(1):445. (SCI)

7.     Lee MG, Lee YK, Huang SC, Chang CL, Ko CY, Lee WC, Chen TY, Tzou SJ, Huang CY, Tai MH, Lin YW, Kung ML, Tsai MC, Chen YL, Chang YC, Wen ZH, Huang CC*, Chu TH*. DLK2 acts as a potential prognostic biomarker for clear cell renal cell carcinoma based on bioinformatics analysis. Genes 2022 Apr;13(4),629. (SCI) (Co-corresponding author)

8.     Huang GK, Huang CC, Kang CH, Cheng YT, Tsai PC, Kao YH, Chung YH. Genetic interference of FGFR3 impedes invasion of upper tract urothelial carcinoma cells by alleviating RAS/MAPK signal activity. Int J Mol Sci 2023 Jan;24(2):1776. (SCI)

9.     Wu JC, Huang CC, Wang PW, Chen TY, Hsu WM, Chuang JH, Chuang HC. ONC201 suppresses neuroblastoma growth by interrupting mitochondrial function and reactivating nuclear ATRX expression while decreasing MYCN. Int J Mol Sci 2023 Jan;24(2):1649. (SCI)

10.  Huang SC*, Huang CC*, Ko CY, Huang CY, Liu CH, Lee YK, Chen TY, Hsueh CW, Tzou SJ, Tai MH, Hu TH, Tsai MC, Lee WC, Ho YC, Wu CC, Chang YC, Chang JJ, Liu KH, Li CC, Wen ZH, Chang CL, Chu TH. Slow skeletal muscle troponin T acts as a potential prognostic biomarker and therapeutic target for hepatocellular carcinoma. Gene 2023 May;865:147331. (SCI) (*Co-first author)