解剖學科

教師資料簡介

姓名: 劉心雲

姓名(英文):Shin Yun Liu

職稱: 助理教授

最高學歷: 國立台灣大學  解剖暨細胞生物學研究所博士

信箱:ShinYunL@cgu.edu.tw

分機:#2649

研究室特色

1.一站式核心技術培訓：融合「細胞實驗」與「動物模型」雙軌訓練，帶你完整走過藥物從細胞測試到動物體內驗證的過程。

2.解鎖實驗技能：獨立操作分子生物學實驗，並掌握免疫學技術，培養帶得走的跨領域研究能力。

3.高含量的轉譯醫學實務：實驗室支持您探索具備臨床醫療潛力的前沿課題。

最近五年所發表論文:

1.Shin-Yun Liu , Chia-Lang Hsu , Shih-Feng Yang , Hsuan-Shu Lee , Jin-Chuan Sheu , Meng-Tzu Weng. Intratumoral administration of poly-ICLC enhances the antitumor effects of anti-PD-1.J Hepatobiliary Pancreat Sci. 2025 Feb;32(2):139-150. (第一作者，IF 3.2)

2.Meng-Tzu Weng , Shin-Yun Liu , Chia-Yueh Hsiung , Meng-Chuan Wu , Tsung-Ying Lee , Been-Ren Lin , Yun-Ching Chen , Shu-Chen Wei. SN38 PLGA nanoparticles provide sustained antitumor efficacy and ameliorate colitis severity in a murine colitis-associated cancer model. International Journal of Pharmaceutics: X\ Volume 11, June 2026, 100552 （IF 7.9 ）

3.Wen-Yun Hsueh, Yi-Ling Wu, Meng-Tzu Weng, Shin-Yun Liu, Jascinta P Santavanond, Yi-Chung Liu, Ching-I Lin, Cheng-Nong Lai, Yi-Ru Lu, Jing Yin Hsu, Hong-Yu Gao,Jinq-Chyi Lee, Shu-Chen Wei, Ping-Chiang Lyu, Ivan K H Poon, Hsing-Pang Hsieh,*and Yu-Hsin Chiu. Novel Naphthyridones Targeting Pannexin 1 for Colitis Management. Adv Sci (Weinh). 2025 Feb;12(7):e2411538. (IF 14.6)

4.Chi-Ting Su, Daniel H.W. See, Yue-Jhu Huang,Tzu-Ming Jao, Shin-Yun Liu , Chih-Yi Chou , Chun-Fu Lai, Wei-Chou Lin, Chih-Yuan Wang, Jenq-Wen Huang, Kuan-Yu Hung. LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts. Circulation Research 2023;133:71-85. (IF 18)

5.Shih-Feng Yang, Meng-Tzu Weng, Ja-Der Liang, Ling-Ling Chiou, Yu-Chen Hsu, Ying-Te Lee, Shin-Yun Liu, Meng-Chuan Wu, Huei-Chi Chou, Li-Fang Wang, Shu-Han Yu, Hsuan-Shu Lee, Jin-Chuan Sheu. Neoantigen vaccination augments antitumor effects of anti-PD-1 on mouse hepatocellular carcinoma. Cancer Letters 2023 April 18 Volume 563.(IF 10.1)

6. Meng-Tzu Weng, Shih-Feng Yang, Shin-Yun Liu, Yu-Chen Hsu, Meng-Chuan Wu, Huei-Chi Chou, Ling-Ling Chiou, Ja-Der Liang, Li-Fang Wang, Hsuan-Shu Lee, Jin-Chuan Sheu. In situ vaccination followed by intramuscular poly-ICLC injections for the treatment of hepatocellular carcinoma in mouse models. Pharmacological Research 4 January 2023 Volume 188, 2023. (IF 10.5)

7. Maria Janina Carrera Espinoza, Kuen-Song Lin*, Meng-Tzu Weng*, Sikhumbuzo Charles Kunene, You-Sheng Lin, Shin-Yun Liu. Magnetic boron nitride nanosheets-based on pH-responsive smart nanocarriers for the delivery of doxorubicin for liver cancer treatment. Colloids and Surfaces B: Biointerfaces 3 January 2023 Volume 222, 2023, 113129.(*corresponding author, IF 5.6)

8. Ndumiso Vukile Mdlovu, Kuen-Song Lin,* , Meng-Tzu Weng*, You-Sheng Lin, Shin-Yun Liu. Preparation and in-vitro/in-vivo evaluation of doxorubicin-loaded magnetic SBA-15 nanocomposites from rice husk for enhancing therapeutic efficacy. Colloids and Surfaces B:Biointerfaces 10 October 2022 Volume 220, 2022, 112923.( *corresponding author, IF 5.6)

9. Maria Janina Carrera Espinoza, Kuen-Song Lin, Meng-Tzu Weng, Sikhumbuzo Charles Kunene, Shin-Yun Liu, You-Sheng Lin. In vivo and in vitro studies of magnetic silicananocomposites decorated with Pluronic F127 for controlled drug delivery system. Journal of Industrial and Engineering Chemistry 25 November 2022, Volume 115, Pages 510-520. (IF 5.9)