Jyh-Ping Chen
Professor
Tel：+886-3-2118800 ext. 5298

Fax: +886-3-2118668

　

　

　
Academic Education 　 　

美國賓州州立大學  

 化工博士   1985-1988      
美國賓州州立大學          化工碩士    1983-1985
國立台灣大學       化工學士      1977-1981
Work Experience 　 　
長庚大學化工與材料工程系 (所) 系主任兼所長 2006-
長庚大學生化與生醫工程研究所工程系   教授兼所長 2002-2006
日本筑波大學基礎醫學研究所 訪問學者 2000
美國明尼蘇達大學化工與材料料學系 訪問教授 1998
長庚大學化工與材料工程系 教授  1997-
長庚大學化工與材料工程系     副教授 1994-1997
國立成功大學化工系 副教授 1991-1994
美國威斯康辛大學乳業研究中心 研究員 1988-1991
美國United Biomedical Inc. 研究員 1987-1988

  

Expertise

生化工程、生醫材料、生物技術、生醫工程、組織工程

                                                      

Research Interests:

(1)    生醫材料與組纖工程

天然與合成高分子生醫材料的開發。包括天然高分子生醫材料的生產、分離純化、加工、與利用具活性的生物分子之修飾。合成高分子生醫材料的化學合成製備、性質分析、與利用電漿反應法改質。利用所得的各式生醫材料為骨架，配合各式生物反應器，進行適用於體內或體外的肝組織工程及軟骨組織工程等研究。

(2)    生化工程

以有機或無機材料進行生物分子、酵素、與細胞的固定化，利用生物催化方式應用於特化品的生產、廢水處理、生化分離、及生醫用途。目前研究工作主要針對各型酯頹、光學活性藥物、生質柴油的生產，藥物制放，人工臟器開發、及染整廢水脫色。

 Recent Publications

  1. Y.H. Ma, S.Y. Wu, T. Wu, Y.J. Chang, M.Y. Hua, J.P. Chen.* 2009. Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles. Biomaterials, in press. (*Corresponding author)

  2. J.P. Chen, S.F. Li and Y.P. Chiang. 2009. Bioactive collagen-grafted poly-L-lactic acid nanofibrous membrane for cartilage tissue engineering. Journal of Nanoscience and Nanotechnology, in press.

  3. B.R. Huang, P.Y. Chen, C.Y. Huang, J.P. Chen,* S.M. Jung, Y.H. Ma, T. Wu, K.C. Wei. 2009. The bioavailability of magnetic nanoparticles to the brain. Journal of Magnetism and Magnetic Materials, in press. (*Corresponding author)

  4. J.P. Chen and T.H. Cheng. 2009. Preparation and evaluation of thermo-reversible copolymer hydrogels containing chitosan and hyaluronic acid as injectable cell carriers. Polymer, 50, 107-116.

  5. J.P. Chen, and T.F. Yang. 2008. Applications of chitosan-based thermo-sensitive copolymers for harvesting living cell sheet. Applied Surface Science, 255, 297-300.

  6. J.P. Chen and W.L. Lee. 2008. Collagen-grafted temperature-responsive nonwoven fabric for wound dressing. Applied Surface Science, 255, 412–415.

  7. J.P. Chen, K.W. Wu and H. Fukuda. 2008. Bioethanol production from uncooked raw starch by immobilized surface-engineered yeast cells. Applied Biochemistry and Biotechnology, 145, 59-67.

  8. J.P. Chen and T.H. Cheng. 2008. Functionalized temperature-sensitive copolymer for tissue engineering of articular cartilage and meniscus. Colloids and Surfaces A: Physicochem. Eng., 313-314, 254-259.

  9. J.P. Chen, G.Y. Chang, J.K. Chen. 2008. Electrospun collagen/chitosan nanofibrous membrane as wound dressing. Colloids and Surfaces A: Physicochem. Eng. Aspects, 313-314, 183-188.

  10. J.P. Chen and Y.S. Lin. 2007. Decolorization of azo dye by immobilized Pseudomonas luteola entrapped in alginate–silicate sol–gel beads. Process Biochemistry, 42, 934-942.

  11. S.F. Li, J.P. Chen,* and W.T. Wu. 2007. Electrospun polyacrylonitrile nanofibrous membranes for lipase immobilization. Journal of Molecular Catalysis B: Enzymatic, 47, 117–124. (*Corresponding author)

  12. J.P. Chen and T. H. Cheng. 2006. Thermo-responsive chitosan-graft-poly(N- isopropylacrylamide) injectable hydrogel for cultivation of chondrocytes and meniscus cells. Macromolecular Bioscience, 6, 1026–1039.

  13. J.P. Chen and C.T. Lin. 2006. Dynamic seeding and perfusion culture of hepatocytes with galactosylated vegetable sponge in a packed-bed bioreactor. Journal of Bioscience and Bioengineering, 102, 41-45.

  14. J.P. Chen and T.C. Lin. 2006. High density culture of hepatocytes in a packed-bed bioreactor usign a fibrous scaffold from plant. Biochemical Engineering Journal, 30, 192-198.

  15. J.P. Chen and Y.P. Chiang. 2006. Surface modification of non-woven fabric by DC pulsed plasma treatment and graft polymerization with acrylic acid. Journal of Membrane Science, 270, 212-220.

  16. J.P. Chen and T.C. Lin. 2005. Loofa sponge as a scaffold for culture of rat hepatocytes. Biotechnology Progress, 21, 315-319.